Skip to Content
MilliporeSigma
All Photos(1)

Documents

213691

Sigma-Aldrich

1,2-Hexanediol

98%

Synonym(s):

1,2-Dihydroxyhexane, 1,2-Hexyleneglycol, 5,6-Dihydroxyhexane, DL-1,2-Hexanediol, Dermasoft Hexiol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3(CH2)3CH(OH)CH2OH
CAS Number:
Molecular Weight:
118.17
Beilstein/REAXYS Number:
1719244
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

liquid

refractive index

n20/D 1.442 (lit.)

bp

223-224 °C (lit.)

density

0.951 g/mL at 25 °C (lit.)

SMILES string

CCCCC(O)CO

InChI

1S/C6H14O2/c1-2-3-4-6(8)5-7/h6-8H,2-5H2,1H3

InChI key

FHKSXSQHXQEMOK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

1,2-Hexanediol acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles. Solubility of 1,2-hexanediol in supercritical CO2 has been reported. It has a tendency of self-association to form micelle-like aggregates.

Application

1,2-Hexanediol can be used in the ruthenium-catalyzed synthesis of oxazolidin-2-ones from urea. It can undergo ruthenium-hydride catalyzed dehydrative coupling with anilines to form substituted indole and quinoline products.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

251.6 °F - closed cup

flash_point_c

122 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

(Enantio) selective Hydrogen Autotransfer: Ruthenium?Catalyzed Synthesis of Oxazolidin?2?ones from Urea and Diols.
Pe?a?Lopez M, et al.
Angewandte Chemie (International Edition in English), 55(27), 7826-7830 (2016)
Ultrasonic absorption studies of surfactant exchange between micelles and bulk phase in aqueous micellar solutions of nonionic surfactants with short alkyl chains. 1. 1, 2-Hexanediol and 1, 2, 3-octanetriol.
Frindi M, et al.
The Journal of Physical Chemistry, 95(12), 4832-4837 (1991)
Sooho Yeo et al.
Pharmaceutics, 13(1) (2021-01-01)
Adenosine (AD), which is used for treating wrinkles, exhibits poor skin permeation. The aim of the present study was to develop a cross-linked silicone-based cellulose elastomer as an elastic artificial skin for the treatment of skin wrinkles, a biocompatible lipid-based
Solubilities of (1-hexanol, or 1, 2-hexanediol, or 2-hydroxypropanoic acid ethyl ester, or 2-hydroxyhexanoic acid ethyl ester) in supercritical CO2.
Chylinski K and Gregorowicz J.
The Journal of Chemical Thermodynamics, 30(9), 1131-1140 (1998)
Catalytic Synthesis of Substituted Indoles and Quinolines from the Dehydrative C?H Coupling of Arylamines with 1, 2-and 1, 3-Diols.
Lee H and Yi C S
Organometallics, 35(11), 1973-1977 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service