Tetraphenylphosphonium bromide


Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
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PubChem Substance ID:
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Quality Level




295-300 °C (lit.)

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Supporting electrolyte for the electroreduction of buckminsterfullerene.


25, 100 g in poly bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

The Journal of Physical Chemistry, 96, 7137-7137 (1992)
Gagandeep S Gurm et al.
JACC. Cardiovascular imaging, 5(3), 285-292 (2012-03-17)
This study tested the hypothesis that 4-[(18)F]fluorophenyltriphenylphosphonium ((18)F-TPP) is useful for in vivo positron emission tomography (PET) measurement of mitochondrial membrane potential (ΔΨm). Its utility as a blood flow tracer also was evaluated. Tetraphenylphosphonium is useful for in vitro measurement...
Avi Swed et al.
Molecular pharmaceutics, 6(6), 1883-1890 (2009-09-03)
Tetraphenylphosphonium (TPP), a phosphonium cation, is a promising means for tumor imaging. A major contributor to the pharmacokinetics of phosphonium cations is the efflux transporter P-glycoprotein (P-gp). For this application it is important to ascertain the influence of the multidrug...
L A Vasil'ev et al.
Biochemistry. Biokhimiia, 77(4), 354-361 (2012-07-20)
Tetraphenylphosphonium (TPP(+)) and tetramethylrhodamine ethyl ester (TMRE(+)) cations used as transmembrane carriers of ubiquinone (MitoQ) and plastoquinone (SkQ, SkQR) in mitochondria prevented at nanomolar concentrations the chitosan- or H(2)O(2)-induced destruction of the nucleus in epidermal cells of epidermis isolated from...
Fedor F Severin et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(2), 663-668 (2010-01-19)
A unique phenomenon of mitochondria-targeted protonophores is described. It consists in a transmembrane H(+)-conducting fatty acid cycling mediated by penetrating cations such as 10-(6'-plastoquinonyl)decyltriphenylphosphonium (SkQ1) or dodecyltriphenylphosphonium (C(12)TPP). The phenomenon has been modeled by molecular dynamics and directly proved by...

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