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Sigma-Aldrich

(S)-(−)-2-Hydroxyisocaproic acid

98%

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Synonym(s):
2-Hydroxy-4-methylvaleric acid, L-2-Hydroxy-4-methylpentanoic acid, L-Leucic acid
Linear Formula:
(CH3)2CHCH2CH(OH)CO2H
CAS Number:
Molecular Weight:
132.16
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

optical activity

[α]22/D −26.3°, c = 1 in 1 M NaOH

mp

78-80 °C (lit.)

SMILES string

CC(C)C[C@H](O)C(O)=O

InChI

1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t5-/m0/s1

InChI key

LVRFTAZAXQPQHI-YFKPBYRVSA-N

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This Item
H9633O6254219819
L-Homocysteic acid ≥95%

Sigma-Aldrich

H9633

L-Homocysteic acid

form

powder

form

powder

form

(powder to crystals)

form

-

mp

78-80 °C (lit.)

mp

-

mp

-

mp

78-80 °C (lit.)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

optical activity

[α]22/D −26.3°, c = 1 in 1 M NaOH

optical activity

-

optical activity

-

optical activity

-

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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L-Leucine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

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Charles H Lang et al.
American journal of physiology. Endocrinology and metabolism, 305(3), E416-E428 (2013-06-13)
Muscle disuse atrophy is observed routinely in patients recovering from traumatic injury and can be either generalized resulting from extended bed rest or localized resulting from single-limb immobilization. The present study addressed the hypothesis that a diet containing 5% α-hydroxyisocaproic
Takayoshi Awakawa et al.
Nature communications, 9(1), 3534-3534 (2018-09-01)
Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions.
Fernanda U Fontella et al.
Metabolic brain disease, 17(1), 47-54 (2002-03-16)
In this study we investigated the in vitro effects of the metabolites accumulating in maple syrup urine disease on lipid peroxidation in brain of young rats. Chemiluminescence and thiobarbituric acid-reactive substances were measured in brain homogenates from 7- and 30-day-old
Antti A Mero et al.
Journal of the International Society of Sports Nutrition, 7, 1-1 (2010-01-07)
Alfa-Hydroxy-isocaproic acid (HICA) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. According to the clinical and experimental studies, HICA can be considered as an anti-catabolic substance. The present study investigated the effects
Continuous enzymatically catalyzed production of L-leucine from the corresponding racemic hydroxy acid.
B Bossow et al.
Annals of the New York Academy of Sciences, 506, 325-336 (1987-01-01)

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