4-Nitrobenzyl chloroformate

Name: 4-Nitrobenzyl chloroformate
Brand: ALDRICH
Price: 53.6 USD

97%, for peptide synthesis

Synonym(s):

(4-Nitrophenyl)methyl carbonochloridate, (4-Nitrophenyl)methyl chloroformate, 4-Nitrobenzyloxycarbonyl chloride, p-Nitrobenzyloxycarbonyl chloride, p-nitrobenzyl chloroformate

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About This Item

Linear Formula:

ClCO₂CH₂C₆H₄NO₂

CAS Number:

4457-32-3

Molecular Weight:

215.59

NACRES:

NA.22

PubChem Substance ID:

24853356

UNSPSC Code:

12352101

EC Number:

224-708-6

MDL number:

MFCD00007375

Beilstein/REAXYS Number:

912446

Key Documents

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Product Name

4-Nitrobenzyl chloroformate, 97%

InChI key

MHSGOABISYIYKP-UHFFFAOYSA-N

InChI

1S/C8H6ClNO4/c9-8(11)14-5-6-1-3-7(4-2-6)10(12)13/h1-4H,5H2

SMILES string

[O-][N+](=O)c1ccc(COC(Cl)=O)cc1

assay

97%

reaction suitability

reaction type: Carbonylations

mp

32-34 °C (lit.)

application(s)

peptide synthesis

functional group

chloro, nitro

storage temp.

2-8°C

Quality Level

200

Related Categories

Building Blocks, Resins, and Coupling Reagents for GLP-1 Synthesis

Amino Acids, Resins & Reagents for Peptide Synthesis

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1 of 4

This Item	420069	8.20272	112208
Sigma-Aldrich 222801 4-Nitrobenzyl chloroformate	Sigma-Aldrich 420069 4,5-Dimethoxy-2-nitrobenzyl chloroformate	Sigma-Aldrich 8.20272 4-Nitrophenyl chloroformate	Sigma-Aldrich 112208 4-Nitrobenzoyl chloride
assay 97%	assay 97%	assay -	assay 98%
functional group chloro, nitro	functional group chloro, nitro	functional group -	functional group acyl chloride, nitro
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. -
mp 32-34 °C (lit.)	mp 125 °C (dec.) (lit.)	mp 78-81 °C	mp 71-74 °C (lit.)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
reaction suitability reaction type: Carbonylations	reaction suitability -	reaction suitability reaction type: Carbonylations	reaction suitability -

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H314,H335

pcodes

P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Hypoxia-responsive folic acid conjugated glycol chitosan nanoparticle for enhanced tumor targeting treatment.

Eun Hyang Jang et al.

International journal of pharmaceutics, 580, 119237-119237 (2020-03-24)

Hypoxia is a characteristic feature of various ischemic diseases, including cancer. This study describes the development of glycol chitosan nanoparticles, hydrophobically modified with 4-nitrobenzyl chloroformate and folic acid (FA), that can specifically release drugs under hypoxic conditions. This hypoxia-responsive glycol

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4-Nitrobenzyl chloroformate