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Key Documents

234311

Sigma-Aldrich

Squalane

96%

Synonym(s):

2,6,10,15,19,23-Hexamethyltetracosane, Cosbiol, Perhydrosqualene, Robane

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About This Item

Linear Formula:
[(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2-]2
CAS Number:
Molecular Weight:
422.81
Beilstein/REAXYS Number:
776019
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

96%

refractive index

n20/D 1.452 (lit.)

bp

176 °C/0.05 mmHg (lit.)

mp

−38 °C (lit.)

solubility

chloroform: soluble 100 mg/mL, clear

density

0.81 g/mL at 25 °C (lit.)

SMILES string

CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C

InChI

1S/C30H62/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h25-30H,9-24H2,1-8H3

InChI key

PRAKJMSDJKAYCZ-UHFFFAOYSA-N

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General description

Dielectrophoretic deformation of thin liquid fillm of squalane has been investigated. Microfluidized squalenes are efficient adjuvants, eliciting both humoral and cellular immune responses.

Application

Squalane has been used:
  • as solvent in the synthesis of Europium dibenzoylmethide triethylammonium, brightest known triboluminescent (TL) material
  • as lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

424.4 °F - closed cup

flash_point_c

218 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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A C Allison
Methods (San Diego, Calif.), 19(1), 87-93 (1999-10-20)
Microfluidized squalene or squalane emulsions are efficient adjuvants, eliciting both humoral and cellular immune responses. Microfluidization stabilizes the emulsions and allows sterilization by terminal filtration. The emulsions are stable for years at ambient temperature and can be frozen. Antigens are
Dielectrophoretic deformation of thin liquid films induced by surface charge patterns on dielectric substrates.
Berendsen CWJ, et al.
Soft Matter, 9(19), 4900-4910 (2013)
Michael Doig et al.
Langmuir : the ACS journal of surfaces and colloids, 30(1), 186-195 (2013-12-25)
The structure and friction of fatty acid surfactant films adsorbed on iron oxide surfaces lubricated by squalane are examined using large-scale molecular dynamics simulations. The structures of stearic acid and oleic acid films under static and shear conditions, and at
Shinya Kato et al.
Journal of biomedical nanotechnology, 6(1), 52-58 (2010-05-27)
We dissolved fullerene-C60 in squalane (LipoFullerene; LF-SQ, C60-eq.: 500 ppm) and examined its defensive effects against 2,4-nonadienal (NDA)-induced cell injury in HaCaT keratinocytes and wrinkle formation in three dimensional (3D)-human skin tissue model. NDA is an analog of 4-hydroxynonenal, one
Aliasgar Shahiwala et al.
Journal of drug targeting, 16(4), 302-310 (2008-05-01)
The objective of this study was to develop and evaluate squalane oil-containing water-in-oil-in-water (W/O/W) multiple emulsion for mucosal administration of ovalbumin (OVA) as a model candidate vaccine in BALB/c mice. Control and optimized OVA-containing W/O/W emulsion (OVA-Emul) and chitosan-modified W/O/W

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