236330

p-Toluenesulfonamide

ReagentPlus^®, ≥99%

• Synonym(s): 4-Methylbenzene-1-sulfonamide, p-Tosylamide
• Linear Formula: CH₃C₆H₄SO₂NH₂
• CAS Number: 70-55-3
• Molecular Weight: 171.22
• Beilstein: 472689
• EC Number: 200-741-1
• MDL number: MFCD00011692
• PubChem Substance ID: 24854164
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥99%
• form: solid
• mp: 134-137 °C (lit.)
• SMILES string: Cc1ccc(cc1)S(N)(=O)=O
• InChI: 1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)
• InChI key: LMYRWZFENFIFIT-UHFFFAOYSA-N
• Gene Information: human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238)

Description

General description

Cyanomethylenetributylphosphorane (CMBP)-mediated reaction of p-toluenesulfonamide with alcohols has been investigated.

Application

p-Toluenesulfonamide has been employed:

• as nucleophile during tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening reaction
• as reagent during selective aziridination of olefins catalyzed by dirhodium (II) caprolactamate

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 395.6 °F - closed cup
• Flash Point(C): 202 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves