Niacinamide, Vitamin PP, Nicotinic acid amide, Vitamin B3, Pyridine-3-carboxylic acid amide
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128-131 °C (lit.)

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Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

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Mitchell E Horwitz et al.
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Sirtuins, a family of histone deacetylases, have a fiercely debated role in regulating lifespan. In contrast with recent observations, here we find that overexpression of sir-2.1, the ortholog of mammalian SirT1, does extend Caenorhabditis elegans lifespan. Sirtuins mandatorily convert NAD(+)...
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