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MilliporeSigma

240230

Phthalimide

≥99%

Synonym(s):

1,3-Dihydro-1,3-dioxoisoindole

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50 G

$15.20

250 G

$37.00

1 KG

$91.40

$15.20


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About This Item

Empirical Formula (Hill Notation):
C8H5NO2
CAS Number:
Molecular Weight:
147.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-603-3
Beilstein/REAXYS Number:
118522
MDL number:
Assay:
≥99%

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InChI key

XKJCHHZQLQNZHY-UHFFFAOYSA-N

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)

SMILES string

O=C1NC(=O)c2ccccc12

assay

≥99%

Quality Level

solubility

water: slightly soluble(lit.)

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1 of 4

This Item
160385P3880379790
assay

≥99%

assay

98%

assay

99%

assay

≥99.0% (NT)

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

200

solubility

water: slightly soluble(lit.)

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

solubility

-

solubility

-

mp

232-235 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

Application

Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method[1].

wgk

WGK 1

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

Storage Class

11 - Combustible Solids


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Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Ive Hermans et al.
Physical chemistry chemical physics : PCCP, 10(8), 1125-1132 (2008-02-14)
Abstraction of hydrogen atoms by pthalimide-N-oxyl radicals is an important step in the N-hydroxyphthalimide catalyzed autoxidation of hydrocarbons. In this contribution, the temperature dependency of this reaction is evaluated by a detailed transition state theory based kinetic analysis for the
Shi Tang et al.
Organic letters, 10(6), 1179-1182 (2008-02-23)
A novel palladium-catalyzed intermolecular aminopalladation/C-H activation method for selectively synthesizing (E)-(2-oxindolin-3-ylidene)phthalimides has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, alkynes were difunctionalized with a phthalimide and an arene sp2 C-H bond to selectively synthesize (E)-(2-oxoindolin-3-ylidene)phthalimides, which products are
Edward C Lawson et al.
Journal of medicinal chemistry, 52(23), 7432-7445 (2009-09-08)
We have discovered two related chemical series of nonpeptide urotensin-II (U-II) receptor antagonists based on piperazino-phthalimide (5 and 6) and piperazino-isoindolinone (7) scaffolds. These structure types are distinctive from those of U-II receptor antagonist series reported in the literature. Antagonist

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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