241571

Quinoline

reagent grade, 98%

• Synonym(s): 1-Benzazine, 2,3-Benzopyridine
• Empirical Formula (Hill Notation): C₉H₇N
• CAS Number: 91-22-5
• Molecular Weight: 129.16
• Beilstein: 107477
• EC Number: 202-051-6
• MDL number: MFCD00006736
• PubChem Substance ID: 24854491
• NACRES: NA.23

Properties

• grade: reagent grade
• Quality Level: 200
• vapor density: 4.5 (vs air)
• vapor pressure: 0.07 mmHg ( 20 °C)
• Assay: 98%
• form: liquid
• autoignition temp.: 896 °F
• refractive index: n20/D 1.625 (lit.)
• bp: 113-114 °C/11 mmHg (lit.); 237 °C (lit.)
• mp: −17-−13 °C (lit.)
• density: 1.093 g/mL at 25 °C (lit.)
• SMILES string: c1ccc2ncccc2c1
• InChI: 1S/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H
• InChI key: SMWDFEZZVXVKRB-UHFFFAOYSA-N
• Gene Information: human ... CYP2D6(1565)

Description

General description

Quinoline is a heterocyclic aromatic organic compound with the chemical formula C₉H₇N.Quinoline derivatives are prevalent in a variety of pharmacologically active synthetic and natural compounds. Quinolines have antiseptic, antipyretic, and antiperiodic properties and are used as antimalarials and for preparing other antimalarial drugs.

Application

Quinoline and its derivatives are widely used as fungicides, biocides, antibiotics, alkaloids, dyes, rubber chemicals, and flavoring agents. Additional industrial applications include their use as corrosion inhibitors, preservatives, and as solvents for resins and terpenes, and in transition-metal complex catalysis for uniform polymerization and luminescence chemistry. They are also used in manufacturing oil soluble dyes, food colorants, pharmaceuticals, pH indicators and other organic compounds. Quinoline is a catabolite of tryptophan, a fundamental structure in some antihypertensive agents such as the peripheral vasodilators prazosin and doxazosin.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301 - H312 - H315 - H319 - H341 - H350 - H411
• Precautionary Statements: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 2 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 213.8 °F - closed cup
• Flash Point(C): 101 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves