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243213

Sigma-Aldrich

Carnauba wax No. 1 yellow

refined

Synonym(s):
Brazil wax
CAS Number:
EC Number:
MDL number:
NACRES:
NA.23

Quality Level

form

powder

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General description

Carnauba wax No.1 yellow(CW) is an ester based wax that can be extracted from palm leaves. The composition of this wax contains aliphatic esters, ω-hydroxy esters and unsaturated alcohols. It can be used as a glossing agent in a variety of pharmaceutical products.

Application

CW may be used as a hydrophobic excipient which can be used to modify the kinetics of polymeric gel in a drug releasing system. It can be used in dry polymeric coatings which can increase the crystallization and improve the stability of amorphous solid drug formulations. It may also be used as a component of lipids which can be used to tune and improve the flowability and designing of solid drugs.

Packaging

250 g in poly bottle
1 kg in poly bottle

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Carnauba wax as a promising excipient in melt granulation targeting the preparation of mini-tablets for sustained release of highly soluble drugs.
Nart V, et al.
Materials Science and Engineering, C, 70(6), 250-257 (2017)
Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1. Microcalorimetric investigation.
Em?s M and Nyqvist H
International Journal of Pharmaceutics, 197(1-2), 117-127 (2000)
Enhanced physical stability of amorphous drug formulations via dry polymer coating.
Capece M and Dave R
Journal of Pharmaceutical Sciences, 104(6), 2076-2084 (2015)
Effect of hydrophobic inclusions on polymer swelling kinetics studied by magnetic resonance imaging.
Gajdosova M, et al
International Journal of Pharmaceutics, 500(1-2), 136-143 (2016)
J R Villalobos-Hernández et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 63(2), 115-127 (2006-04-20)
Aqueous nanoscale lipid dispersions consisting of carnauba wax-decyl oleate mixtures acting as carriers or accompanying vehicles for inorganic sunscreens such as barium sulfate, strontium carbonate, and titanium dioxide were prepared by high pressure homogenization. For the manufacture of these nanosuspensions

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