243299

1-Bromo-2-butanone

95%

• Synonym(s): Bromomethyl ethyl ketone
• Linear Formula: C₂H₅COCH₂Br
• CAS Number: 816-40-0
• Molecular Weight: 151.00
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854607
• EC Number: 212-431-3
• MDL number: MFCD00000207
• Assay: 95%
• Form: liquid

Properties

• assay: 95%
• form: liquid
• contains: ~5% calcium carbonate as stabilizer
• refractive index: n20/D 1.465 (lit.)
• bp: 105 °C/150 mmHg (lit.)
• density: 1.479 g/mL at 25 °C (lit.)
• storage temp.: −20°C
• SMILES string: CCC(=O)CBr
• InChI: 1S/C4H7BrO/c1-2-4(6)3-5/h2-3H2,1H3
• InChI key: CCXQVBSQUQCEEO-UHFFFAOYSA-N

Description

Application

1-Bromo-2-butanone (bromomethyl ethyl ketone) was used as a potential regulatory site-directed reagent for the residue C221 on pyruvate decarboxylase. It was also used as a reagent for aromatic bromination with sodium hydride in DMSO and in a microwave-assisted preparation of fused heterocycles.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302 + H312 + H332,H315,H319,H335
• Precautionary Statements: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 154.4 °F - closed cup
• Flash Point (°C): 68 °C - closed cup
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter