249467

Sigma-Aldrich

Propyl chloroformate

98%

Linear Formula:
ClCO2CH2CH2CH3
CAS Number:
Molecular Weight:
122.55
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

0.87 psi ( 20 °C)

Quality Level

assay

98%

refractive index

n20/D 1.404 (lit.)

bp

105-106 °C (lit.)

solubility

benzene: miscible(lit.)
chloroform: miscible(lit.)
diethyl ether: miscible(lit.)

density

1.09 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCCOC(Cl)=O

InChI

1S/C4H7ClO2/c1-2-3-7-4(5)6/h2-3H2,1H3

InChI key

QQKDTTWZXHEGAQ-UHFFFAOYSA-N

Related Categories

Application

Propyl chloroformate has been used:
  • as derivatization reagent in quantification of dopamine, serotonin and norepinephrine in human urine by solid phase microextraction-gas chromatography-triple quadrupole mass spectrometry
  • in the preparation of dipropyl 3,6-diphenyl-1,2-dihydro-1,2,4,5-tetrazine-1,2-dicarboxylate

Packaging

25, 100 g in glass bottle

Signal Word

Danger

Hazard Statements

hazcat

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 1

Flash Point(F)

71.6 °F

Flash Point(C)

22 °C

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Jake P Violi et al.
Ecotoxicology and environmental safety, 172, 72-81 (2019-01-27)
Environmental exposure to the amino acid β-methylamino-L-alanine (BMAA) was linked to the high incidence of neurodegenerative disease first reported on the island of Guam in the 1940s and has more recently been implicated in an increased incidence of amyotrophic lateral...
Guo-Wu Rao et al.
Acta crystallographica. Section C, Crystal structure communications, 59(Pt 5), o281-o282 (2003-05-14)
The title compound, C(22)H(24)N(4)O(4), was prepared from propyl chloroformate and 3,6-diphenyl-1,2-dihydro-s-tetrazine. This reaction yields the title compound rather than dipropyl 3,6-diphenyl-1,4-dihydro-s-tetrazine-1,4-dicarboxylate. The 2,3-diazabutadiene group in the central six-membered ring is not planar; the C=N double-bond length is 1.285 (2) A...
Yingmei Dong et al.
Frontiers in pharmacology, 11, 549-549 (2020-05-21)
Dysbiosis of gut microbiota is a critical factor in the pathogenesis of asthma. Manipulating gut microbiota is a promising therapeutic intervention in asthma, and is being extensively studied. Gu-Ben-Fang-Xiao Decoction (GBFXD), derived from traditional Chinese medicine, is an effective and...
Yixing Sui et al.
Bioresource technology, 275, 145-152 (2018-12-26)
The microalga Dunaliella salina has been widely studied for carotenogenesis, yet its protein production for human nutrition has rarely been reported. This study unveils the effects of growth phase and light regime on protein and essential amino acid (EAA) levels...
Brendan J Main et al.
Harmful algae, 74, 10-18 (2018-05-05)
The emerging toxin β-methylamino-l-alanine (BMAA) has been linked to the development of a number of neurodegenerative diseases in humans including amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and Parkinson's disease. BMAA has been found to be produced by a range of...

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