256226

Sigma-Aldrich

N,N-Dimethyloctylamine

95%

Synonym(s):
DMOA, Adma 8, N-Octyldimethylamine, 1-(Dimethylamino)octane
Linear Formula:
CH3(CH2)7N(CH3)2
CAS Number:
Molecular Weight:
157.30
Beilstein/REAXYS Number:
1698081
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

vapor density

5.4 (vs air)

Quality Level

vapor pressure

0.8 mmHg ( 25 °C)

assay

95%

refractive index

n20/D 1.424 (lit.)

bp

195 °C (lit.)

mp

−57 °C (lit.)

density

0.765 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCN(C)C

InChI

1S/C10H23N/c1-4-5-6-7-8-9-10-11(2)3/h4-10H2,1-3H3

InChI key

UQKAOOAFEFCDGT-UHFFFAOYSA-N

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Application

N,N-Dimethyloctylamine has been employed:
  • as ion-pairing agent in quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC
  • as counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography
  • as mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide in human plasma
  • in study of chiral separations by complexation with proteins in capillary zone electrophoresis

Packaging

5, 25, 100 mL in glass bottle

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

T

Risk Statement

25-37/38-41

Safety Statement

26-39-45

RIDADR

UN 2922 6.1(8) / PGIII

WGK Germany

WGK 1

Flash Point(F)

156.2 °F - closed cup

Flash Point(C)

69 °C - closed cup

E Smet et al.
Journal of pharmaceutical and biomedical analysis, 23(1), 175-183 (2000-07-18)
The phenothiazine derivative thiazinamium methylsulphate is a drug with antihistaminic and anticholinergic properties, often used in some types of obstructive lung diseases. Because there is a lack of chromatographic data available for its determination, the objective of the present investigation...
J Hermansson et al.
Journal of chromatography, 336(2), 321-328 (1984-12-12)
The direct resolution and quantitation of (R)- and (S)-disopyramide, isolated from human plasma, was accomplished using a chiral alpha 1-acid glycoprotein column. A LiChrosorb RP-2 column (50 X 3.0 mm I.D.) was used as a precolumn. Phosphate buffer, pH 6.20...
J Hermansson et al.
Journal of pharmaceutical sciences, 71(2), 222-229 (1982-02-01)
Methods are presented for the separation of tetracycline, tetracycline analogs, and their potential impurities by reversed-phase ion-pair chromatography. The mobile phase consisted of a phosphate buffer with tripropylamine or N,N-dimethyloctylamine as counterions and acetonitrile as the organic modifier. The chromatographic...
Journal of Chromatography A, 635, 119-119 (1993)
T T Nikiforov et al.
Analytical biochemistry, 227(1), 201-209 (1995-05-01)
A reliable, simple, and cost-effective method for the immobilization of relatively short (12-30 mer) oligonucleotide probes to 96-well polystyrene plates was required in our laboratory for use in DNA hybridization-based assays. We compared three different approaches to achieve this immobilization....

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