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268119

Sigma-Aldrich

Diethyl methylphosphonate

97%

Synonym(s):
Bis(diethoxyphosphinyl)methane, DEMP, Diethoxymethylphosphine oxide
Linear Formula:
CH3P(O)(OC2H5)2
CAS Number:
Molecular Weight:
152.13
Beilstein:
1753416
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

reaction suitability

reaction type: C-C Bond Formation

refractive index

n20/D 1.414 (lit.)

bp

194 °C (lit.)

density

1.041 g/mL at 25 °C (lit.)

SMILES string

CCOP(C)(=O)OCC

InChI

1S/C5H13O3P/c1-4-7-9(3,6)8-5-2/h4-5H2,1-3H3

InChI key

NYYLZXREFNYPKB-UHFFFAOYSA-N

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This Item
D91705158763D91071
assay

97%

assay

98%

assay

97%

assay

99%

reaction suitability

reaction type: C-C Bond Formation

reaction suitability

reaction type: C-C Bond Formation

reaction suitability

reaction type: C-C Bond Formation

reaction suitability

reaction type: C-C Bond Formation

refractive index

n20/D 1.414 (lit.)

refractive index

n20/D 1.434 (lit.)

refractive index

n20/D 1.433 (lit.)

refractive index

n20/D 1.497 (lit.)

bp

194 °C (lit.)

bp

101-102 °C/0.4 mmHg (lit.)

bp

127-131 °C/9 mmHg (lit.)

bp

106-108 °C/1 mmHg (lit.)

density

1.041 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

density

1.145 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Application

Reactant for the synthesis of:
  • Fluoroalkyl α- and β-aminophosphonates
  • Acyclic nucleoside phosphonates with branched phosphonoethoxy-Et chains as potential antivirals
  • Difluoromethyl arylphosphonates
  • Pyridone alkaloids with neuritogenic activity
  • Lipophilic meropenem-derived prodrugs
  • Phomactin cyclohexane core and diterpenoid framework
  • Phosphonylated peptides via solid-phase synthesis
Reagent employed in the synthesis of α-alkenyl, γ-hydroxyl, and dialkyl fluoroalkynyl phosphonates.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

167.0 °F - closed cup

Flash Point(C)

75 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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