(S)-(+)-2-Phenylglycinol

Name: (<I>S</I>)-(+)-2-Phenylglycinol
Brand: ALDRICH
Price: 28.5 USD
Availability: InStock

98%, for peptide synthesis

Synonym(s):

(S)-2-Amino-2-phenylethanol, L-(+)-α-Phenylglycinol

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Estimated to ship onJanuary 12, 2026Details

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About This Item

Linear Formula:

C₆H₅CH(NH₂)CH₂OH

CAS Number:

20989-17-7

Molecular Weight:

137.18

NACRES:

NA.22

PubChem Substance ID:

24857063

UNSPSC Code:

12352209

MDL number:

MFCD00064404

Beilstein/REAXYS Number:

3196190

Key Documents

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Product Name

(S)-(+)-2-Phenylglycinol, 98%

InChI

1S/C8H11NO/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2/t8-/m1/s1

SMILES string

N[C@H](CO)c1ccccc1

InChI key

IJXJGQCXFSSHNL-MRVPVSSYSA-N

assay

98%

form

solid

optical activity

[α]19/D +33°, c = 0.75 in 1 M HCl

optical purity

ee: 99% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

75-78 °C (lit.)

application(s)

peptide synthesis

Quality Level

200

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

Building Blocks, Resins, and Coupling Reagents for GLP-1 Synthesis

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1 of 4

This Item	190357	429821	237647
Sigma-Aldrich 282693 (S)-(+)-2-Phenylglycinol	Sigma-Aldrich 190357 (R)-(−)-2-Phenylglycinol	Sigma-Aldrich 429821 (+)-N-Boc-L-α-phenylglycinol	Sigma-Aldrich 237647 L−(+)-α-Phenylglycine
form solid	form -	form solid	form powder
assay 98%	assay 98%	assay 99%	assay 99%
optical activity [α]19/D +33°, c = 0.75 in 1 M HCl	optical activity [α]24/D −31.7°, c = 0.76 in 1 M HCl	optical activity [α]19/D +37°, c = 1 in chloroform	optical activity [α]20/D +155°, c = 1 in 1 M HCl
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
mp 75-78 °C (lit.)	mp 75-77 °C (lit.)	mp 136-139 °C (lit.)	mp >300 °C (lit.)
optical purity ee: 99% (GLC)	optical purity ee: 99% (GLC)	optical purity ee: 99% (GLC)	optical purity -

Application

Used in a synthesis of chiral, unsymmetrical bisoxazolines.[1]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Tetrahedron Asymmetry, 17, 2270-2270 (2006)

Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors.

Jin Han et al.

European journal of medicinal chemistry, 124, 583-607 (2016-09-12)

The present study describes our continuous effort to develop epidermal growth factor receptor (EGFR) inhibitors based on the 6-aryl-pyrrolo[2,3-d]pyrimidin-4-amine scaffold. The activity-ADME space has been evaluated by synthesizing 43 new structures, including four variations of the 4-amino group and 34

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(S)-(+)-2-Phenylglycinol