All Photos(1)

283320

Sigma-Aldrich

Butyl lactate

98%

Linear Formula:
CH3CH(OH)CO2(CH2)3CH3
CAS Number:
Molecular Weight:
146.18
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

vapor density

5.04 (vs air)

vapor pressure

0.4 mmHg ( 20 °C)

assay

98%

refractive index

n20/D 1.421 (lit.)

bp

185-187 °C (lit.)

mp

−28 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

SMILES string

CCCCOC(=O)C(C)O

InChI

1S/C7H14O3/c1-3-4-5-10-7(9)6(2)8/h6,8H,3-5H2,1-2H3

InChI key

MRABAEUHTLLEML-UHFFFAOYSA-N

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Application

Butyl lactate has been used:
  • in the preparation of solid lipid nanoparticles by a solvent emulsification–diffusion technique
  • in the synthesis of nanoparticles of griseofulvin from water dilutable microemulsions by the solvent diffusion technique
  • as cosurfactant on the preparation of microemulsions with anionic surfactant

Packaging

2 kg in glass bottle
25, 500 g in glass bottle

Storage Class Code

10 - Combustible liquids

WGK Germany

WGK 2

Flash Point(F)

156.2 °F - closed cup

Flash Point(C)

69 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Microemulsions with butyl lactate as cosurfactant.
<BIG>Comelles F and Pascual A. </BIG>
Journal of Dispersion Science and Technology, 18(2), 161-175 (1997)
Michele Trotta et al.
International journal of pharmaceutics, 257(1-2), 153-160 (2003-04-25)
A preparation method for nanoparticles based on the emulsification of a butyl lactate or benzyl alcohol solution of a solid lipid in an aqueous solution of different emulsifiers, followed by dilution of the emulsion with water, was used to prepare...
Michele Trotta et al.
International journal of pharmaceutics, 254(2), 235-242 (2003-03-08)
Nanoparticles of griseofulvin, a model drug with poor solubility and low bioavailability, were prepared from water dilutable microemulsions by the solvent diffusion technique. Solvent-in-water microemulsion formulations containing water, butyl lactate, lecithin, taurodeoxycholate sodium salt (TDC) or dipotassium glycyrrhizinate (KG), 1,2-propanediol...
Domenico Pirozzi et al.
Biotechnology progress, 22(2), 444-448 (2006-04-08)
The alpha-hydroxy esters are increasingly employed in cosmetic, food, and pharmaceutical formulations as they determine reduced skin-irritant effects in comparison with the respective acids, offering similar hygroscopic, emulsifying, and exfoliating properties. The enzymatic synthesis of lactate esters in nonaqueous systems...
Yunwei Niu et al.
Food research international (Ottawa, Ont.), 131, 108986-108986 (2020-04-06)
Ester aroma compounds in Chinese Moutai Baijiu were extracted by liquid-liquid extraction (LLE) or headspace solid-phase microextraction (HS-SPME) and identified and quantified by gas chromatography-olfactometry (GC-O) and gas chromatography-mass spectrometry (GC-MS), and 13 of them were recognized as the important...

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