283541

Sigma-Aldrich

4-Nitrophenyl isothiocyanate

98%

Linear Formula:
O2NC6H4NCS
CAS Number:
Molecular Weight:
180.18
Beilstein/REAXYS Number:
640027
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

assay

98%

bp

137-138 °C/11 mmHg (lit.)

mp

110-112 °C (lit.)

SMILES string

O-N+(=O)c1ccc(cc1)N=C=S

InChI

1S/C7H4N2O2S/c10-9(11)7-3-1-6(2-4-7)8-5-12/h1-4H

InChI key

NXHSSIGRWJENBH-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

The solid-state reactivity of hydrazine hydrochloride with 4-nitrophenyl isothiocyanate was studied.

Application

4-Nitrophenyl isothiocyanate has been used in the synthesis of:
  • 5,6-dimethyl-2-(4-nitrophenyl)aminothieno2,3-dpyrimidin-4(3H)-one
  • 4,5-dimethyl-2-substituted carbamothioylaminothiophene-3-carboxamides
  • acyclic triazene or zwitterionic dihydropyrimidinium imidothiolate derivatives

Packaging

5, 25 g in glass bottle

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

36/37/38-42

Safety Statement

22-26-36

RIDADR

UN 3335

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Investigation into the reaction of 2-amino-4, 5-dimethylthiophene-3-carboxamide with iso (and isothio) cyanates under microwave irradiation.
Davoodnia A, et al.
Heteroatom Chem., 20(6), 346-349 (2009)
Exploring the nucleophilicity of N, N'-diamidocarbenes: Heteroallenes and related compounds as coupling reagents.
Lee YG, et al.
Journal of Physical Organic Chemistry, 25(11), 1027-1027 (2012)
Solid?state reactivity of the hydrazine?hydroquinone complex.
Kaupp G and Schmeyers J.
Journal of Physical Organic Chemistry, 13(7), 388-394 (2000)
Qian Han et al.
ACS sensors, 4(2), 309-316 (2018-11-06)
An effective bioanalytical method for rapid, sensitive, specific, and in situ sensing of nitric oxide (NO) is the key for further unveiling the biological functions of this gasotransmitter molecule in vitro and in vivo. In this contribution, a new fluorescence...
Nargess Yousefi Limaee et al.
Journal of fluorescence, 30(2), 375-387 (2020-02-23)
Fluorescent molecularly imprinted polymer (FMIP) optosensor was utilized for the selective identification of 2,4-dichlorophenoxacetic acid (2,4-D) due to worldwide pollution caused by using herbicides in agricultural industry. In this regards, two derivatives of polymerizable 1,8-naphthalimide namely, 1,8-naphthalimide containing thiourea (NI)...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.