MilliporeSigma
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286567

Sigma-Aldrich

Mephenesin

98%

Synonym(s):
3-(2-Methylphenoxy)-1,2-propanediol
Linear Formula:
CH3C6H4OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
182.22
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

98%

form

powder

bp

153-154 °C/4 mmHg (lit.)

mp

69-71 °C (lit.)

SMILES string

Cc1ccccc1OCC(O)CO

InChI

1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3

Inchi Key

JWDYCNIAQWPBHD-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Jing Quan et al.
Bioorganic & medicinal chemistry, 15(4), 1741-1748 (2006-12-21)
A facile, high regioselective enzymatic synthesis approach for the preparation of amphipathic prodrugs with saccharides of mephenesin and chlorphenesin was developed. Firstly, transesterification of two drugs with divinyl dicarboxylates with different carbon chain length was performed under the catalysis of
A Schulze-Dirks et al.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 44(6), 403-406 (1993-06-01)
A case of erythema multiforme-like allergic contact dermatitis due to midysalb, an ointment containing mephenesine is described. Patch testing showed marked sensitization to mephenesine, with positive reactions to different dilutions down to 0.1%. It is unlikely that the weak reaction
K Sakitama et al.
Japanese journal of pharmacology, 60(2), 127-131 (1992-10-01)
The effects of morphine-HCl and mephenesin on the flexor reflex mediated by group II afferent fibers were investigated. The flexor reflex was recorded by means of the electromyogram (EMG) evoked in the muscle tibialis anterior by stimulation of the ipsilateral
Nedim Kasumacic et al.
The Journal of physiology, 588(Pt 24), 4905-4925 (2010-10-22)
Proper control of movement and posture occurs partly via descending projections from the vestibular nuclei to spinal motor circuits. Days before birth in rodents, vestibulospinal neurons develop axonal projections that extend to the spinal cord. How functional these projections are
K Sakitama
Japanese journal of pharmacology, 63(3), 369-376 (1993-11-01)
The effects of centrally acting muscle relaxants on the flexor reflex mediated by group II afferent fibers (group II flexor reflex) in anesthetized intact rats and on the intrathecal noradrenaline-HCl-induced facilitation of the group II flexor reflex in anesthetized spinal

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