If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
287067
L-Proline methyl ester hydrochloride
98%, for peptide synthesis
Synonym(s):
(S)-Methyl pyrrolidine-2-carboxylate hydrochloride, L-Pro-OMe HCl
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 g | Available to ship TODAYfromMILWAUKEE | $40.00 $30.00 |
5 g | Available to ship TODAYfromMILWAUKEE | $113.00 $84.75 |
25 g | Available to ship TODAYfromMILWAUKEE | $143.00 |
About This Item
$30.00
List Price$40.00Save 25%Available to ship TODAYDetails
Product Name
L-Proline methyl ester hydrochloride, 98%
Quality Segment
assay
98%
form
solid
optical activity
[α]20/D −31°, c = 0.5 in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
69-71 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl[H].[H][C@]1(CCCN1)C(=O)OC
InChI
1S/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m0./s1
InChI key
HQEIPVHJHZTMDP-JEDNCBNOSA-N
Application
- A building block in peptide synthesis.
- A catalyst to synthesize 3,4-dihydropyrimidin-2-(1H)-ones via Biginelli condensation reaction with aryl aldehydes, methyl acetoacetate, and urea.
- A reactant to prepare prolylproline.
1 of 1
This Item | |||
|---|---|---|---|
| form solid | form powder or crystals | form powder | form powder |
| assay 98% | assay 98% | assay 98% | assay 98% |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
| mp 69-71 °C (lit.) | mp 151-153 °C (lit.) | mp 163 °C (dec.) (lit.) | mp 151-153 °C (lit.) |
| optical activity [α]20/D −31°, c = 0.5 in H2O | optical activity [α]22/D +13°, c = 2 in H2O | optical activity [α]20/D +3.4°, c = 4 in methanol | optical activity [α]22/D +25.9°, c = 1 in H2O |
| reaction suitability reaction type: solution phase peptide synthesis | reaction suitability reaction type: solution phase peptide synthesis | reaction suitability reaction type: solution phase peptide synthesis | reaction suitability reaction type: solution phase peptide synthesis |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
-
How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
-