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290858

Sigma-Aldrich

Nonylphenol

technical grade, mixture of ring and chain isomers

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Empirical Formula (Hill Notation):
C15H24O
CAS Number:
Molecular Weight:
220.35
Beilstein/REAXYS Number:
2047450
EC Number:
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Quality Level

refractive index

n20/D 1.511 (lit.)

solubility

water: slightly soluble 4.9 mg/L±0.4 mg/L

density

0.937 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCc1ccc(O)cc1

InChI

1S/C15H24O/c1-13(2)7-5-3-4-6-8-14-9-11-15(16)12-10-14/h9-13,16H,3-8H2,1-2H3

InChI key

JSFITYFUKSFPBZ-UHFFFAOYSA-N

Gene Information

mouse ... Esr1(13982)
rat ... Ar(24208)

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This Item
460183246832894
Nonylphenol technical grade, mixture of ring and chain isomers

290858

Nonylphenol

Nonylphenol PESTANAL®, analytical standard, technical mixture

46018

Nonylphenol

Nonylphenol solution 1000 μg/mL in acetone, analytical standard

32468

Nonylphenol solution

Nonylphenol monoethoxylate solution 50 μg/mL in acetone, technical, analytical standard

32894

Nonylphenol monoethoxylate solution

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

density

0.937 g/mL at 25 °C (lit.)

density

0.937 g/mL at 25 °C (lit.)

density

-

density

-

refractive index

n20/D 1.511 (lit.)

refractive index

n20/D 1.511 (lit.)

refractive index

-

refractive index

-

grade

technical grade

grade

analytical standard

grade

analytical standard

grade

analytical standard, technical

Gene Information

mouse ... Esr1(13982)
rat ... Ar(24208)

Gene Information

-

Gene Information

-

Gene Information

-

General description

Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. Nonylphenol has been reported as antiandrogen by using a yeast detection system. Molecular mechanism for the antiandrogenic action of nonylphenol has been reported.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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A Soares et al.
Environment international, 34(7), 1033-1049 (2008-02-20)
Nonylphenol is a toxic xenobiotic compound classified as an endocrine disrupter capable of interfering with the hormonal system of numerous organisms. It originates principally from the degradation of nonylphenol ethoxylates which are widely used as industrial surfactants. Nonylphenol ethoxylates reach
Hyun Ju Lee et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 40-46 (2003-06-14)
By using a yeast detection system for androgenic and antiandrogenic effects of chemicals, we identified bisphenol A (BPA) and nonylphenol (NP) as antiandrogens. In this study, we report molecular mechanisms for the antiandrogenic action of BPA and NP. In the
C Uguz et al.
Andrologia, 47(8), 910-919 (2014-10-04)
The objective of this study was to determine the effects of nonylphenol (NP) on viability of ram and boar sperm in vitro. Ram or boar spermatozoa were exposed to 1, 10, 100, 250 and 500 μg NP ml(-1) for 1, 2, 3 or
Maurizio Forte et al.
Ecotoxicology and environmental safety, 180, 412-419 (2019-05-21)
Estrogens play a role in the patho-physiology of the prostate. In the present work we studied the effects of nonylphenol (NP), a xenoestrogen, on human adenocarcinoma prostate cells (LNCaP). In order to understand molecular and cellular involvement, we observed the
Tomasz Janicki et al.
Bioresource technology, 200, 223-229 (2015-10-23)
Nonylphenol (NP), 4-tert-octylphenol (4-t-OP) and 4-cumylphenol (4-CP) are pollutants that are known as endocrine disruptors mainly due to their estrogen-mimicking activity. These phenolic substances are used in a wide range of industrial and commercial applications. In the present study, biodegradation

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