29516

(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine]

≥97% (CHN), optical purity ee: ≥99%

• Synonym(s): SL-A120-1, (R)-2,2′-Bis[bis(3,5-dimethyl)phosphino]-6,6′-dimethoxy-1,1′-biphenyl, (R)-3,5-Xyl-MeOBIPHEP
• Empirical Formula (Hill Notation): C₄₆H₄₈O₂P₂
• CAS Number: 394248-45-4
• Molecular Weight: 694.82
• MDL number: MFCD09753009
• PubChem Substance ID: 329753364
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥97% (CHN)
• optical purity: ee: ≥99%
• SMILES string: COc1cccc(P(c2cc(C)cc(C)c2)c3cc(C)cc(C)c3)c1-c4c(OC)cccc4P(c5cc(C)cc(C)c5)c6cc(C)cc(C)c6
• InChI: 1S/C46H48O2P2/c1-29-17-30(2)22-37(21-29)49(38-23-31(3)18-32(4)24-38)43-15-11-13-41(47-9)45(43)46-42(48-10)14-12-16-44(46)50(39-25-33(5)19-34(6)26-39)40-27-35(7)20-36(8)28-40/h11-28H,1-10H3
• InChI key: IMUHNRWTDUVXOU-UHFFFAOYSA-N

Description

Application

Atropisomeric MeOBIPHEP ligands

(R)-(6,6′-Dimethoxybiphenyl-2,2′-diyl)bis[bis(3,5-dimethylphenyl)phosphine] can be used as a ligand:

• In the synthesis of (S)-3-amino-4-methoxy-butan-1-ol, a key starting material for many pharmaceutical drugs.
• In the synthesis of 3-substituted indanones through the reductive Heck reaction of chalcones with various amines.
• In the palladium-catalyzed Tsuji-Trost cyclizations of aldehydes to yield vinylcyclopentane derivatives.

Packaging

1, 5 g in glass bottle

100, 500 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

sold in collaboration with Solvias AG

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves