Fufeng Liu et al.
ACS chemical neuroscience, 10(1), 588-598 (2018-10-20)
The fibrillogenesis of amyloid-β protein (Aβ) is considered a crucial factor in the pathogenesis of Alzheimer's disease (AD). Hence, inhibiting Aβ fibrillogenesis is regarded as the primary therapeutic strategy for the prevention and treatment of AD. However, the development of...
V Prasanna et al.
Biochemistry, 37(19), 6883-6893 (1998-06-06)
Three synthetic peptides corresponding to distinct segments of the subunit interface of the dimeric enzyme thymidylate synthase (residues 17-38, N 22; residues 174-190, M 17; and residues 201-220, C 20) have been investigated for their ability to function as inhibitors...
"Teflon-coated peptides": hexafluoroacetone trihydrate as a structure stabilizer for peptides.
R Rajan et al.
Biopolymers, 42(2), 125-128 (1997-08-01)
Stefania Albrizio et al.
Journal of medicinal chemistry, 45(4), 762-769 (2002-02-08)
CCK-15, a peptide derived from the 115-membered CCK preprohormone, was the object of a comparative conformational analysis by NMR spectroscopy and molecular modeling methods. NMR data in several solvents demonstrate that the propensity of the peptide to fold into a...
C Geffroy-Rodier et al.
Journal of chromatography. A, 1245, 158-166 (2012-05-29)
Within the perspective of the current and next space missions to Mars (MSL 2011 and Exomars 2016-2018), the detection and enantioselective separation of building blocks such as the amino acids are important subjects which are becoming fundamental for the search...