295590

Sigma-Aldrich

Nitrous oxide

99%

Synonym(s):
Dinitrogen monoxide, Laughing gas
Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein/REAXYS Number:
8137358
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

assay

99%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

  • Nitrous oxide allows selective oxygen atom transfer reactions while minimizing the risk of over-oxidation. Therefore, it is used to oxidize disilenes, silanimines, silaethenes and silylenes.
  • Along with Ru-porphyrin catalyst, it can be used in the epoxidation of olefins and steroids.
  • It can be used as an oxidant in for the metal-catalyzed oxidative homo- and cross-coupling of Grignard reagents.
  • N2O can also be used as a nitrogen-dopant source to synthesize p-type zinc oxide nanowires (ZnO NWs) via vapor-liquid-solid growth.

Packaging

227 g in steel cylinder

Other Notes

For 295590-270G-EU packaging: 400 mL of aluminium cylinder equipped with brass valve.

Recommended products

  • For 295590-270G-EU: outlet fitting is DIN 477-1 no. 1, Z742160 or Z742161 are the recommended regulators.
  • For 295590-227G: Z146706 CGA 180 Regulator OR Z146943 CGA 110 valve with Z147095 CGA 110 to CGA 180 adapter and Z146986 washer for valve.

Pictograms

Flame over circleGas cylinder

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN1070 - class 2 - Nitrous oxide

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Synthetic chemistry with nitrous oxide.
Severin K.
Chemical Society Reviews, 44(17), 6375-6386 (2015)
Nitrous oxide oxidation of olefins catalyzed by ruthenium porphyrin complexes.
Yamada T, et al.
Chemistry Letters (Jpn), 30(3), 268-269 (2001)
Git Lidman et al.
Developmental medicine and child neurology, 57(8), 754-761 (2015-03-27)
To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning...
Klaus Butterbach-Bahl et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1621), 20130122-20130122 (2013-05-29)
Although it is well established that soils are the dominating source for atmospheric nitrous oxide (N2O), we are still struggling to fully understand the complexity of the underlying microbial production and consumption processes and the links to biotic (e.g. inter-...
Philip J Peyton et al.
Anesthesiology, 120(5), 1137-1145 (2014-01-10)
Inclusion of nitrous oxide in the gas mixture has been implicated in postoperative nausea and vomiting (PONV) in numerous studies. However, these studies have not examined whether duration of exposure was a significant covariate. This distinction might affect the future...

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