297682

Sigma-Aldrich

(R)-(−)-2-Amino-1-propanol

98%

Synonym(s):
D-Alaninol
Linear Formula:
CH3CH(NH2)CH2OH
CAS Number:
Molecular Weight:
75.11
Beilstein/REAXYS Number:
1718866
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

98%

optical activity

[α]19/D −18°, neat

optical purity

ee: 97% (GLC)

refractive index

n20/D 1.4493 (lit.)

bp

166-168 °C (lit.)

density

0.963 g/mL at 20 °C (lit.)

SMILES string

C[C@@H](N)CO

InChI

1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m1/s1

InChI key

BKMMTJMQCTUHRP-GSVOUGTGSA-N

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General description

(R)-(-)-2-Amino-1-propanol is a chiral secondary amine.

Application

(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography.

Packaging

1, 5 g in glass bottle

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2735PSN1 8 / PGII

WGK Germany

WGK 3

Flash Point(F)

181.4 °F - closed cup

Flash Point(C)

83 °C - closed cup

A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer.
Schelman WR, et al.
Investigational New Drugs, 32(2), 295-302 (2014)
Determination of (+)-,(-)-, and total gossypol in cottonseed by high-performance liquid chromatography.
Hron RJ, et al.
Journal of the American Oil Chemists' Society, 76(11), 1351-1355 (1999)
A synthetic molecular pentafoil knot.
Ayme J-F, et al.
Nature Chemistry, 4(1), 15-20 (2012)
Neslihan Beyazit et al.
Carbohydrate polymers, 240, 116333-116333 (2020-06-02)
In this work, two new chitosan-Schiff base derivatives (HCS-GSP and LCS-GSP) were synthesized by the condensation reaction of high molecular weight chitosan (HCS) and low molecular weight chitosan (LCS) with (-)-gossypol (GSP), respectively. For this purpose, racemic gossypol was isolated...

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