307882

Sigma-Aldrich

(R)-(−)-2-Phenylglycine methyl ester hydrochloride

≥95%

Linear Formula:
C6H5CH(NH2)CO2CH3·HCl
CAS Number:
Molecular Weight:
201.65
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

≥95%

optical activity

[α]20/D −118°, c = 1 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis: suitable

mp

189-191 °C (lit.)

SMILES string

Cl.COC(=O)[C@H](N)c1ccccc1

InChI

1S/C9H11NO2.ClH/c1-12-9(11)8(10)7-5-3-2-4-6-7;/h2-6,8H,10H2,1H3;1H/t8-;/m1./s1

Inchi Key

DTHMTBUWTGVEFG-DDWIOCJRSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

K Sasaki et al.
Bioscience, biotechnology, and biochemistry, 61(10), 1783-1785 (1997-11-15)
The absolute configuration of pectenotoxin-6 (4, PTX6), found in association with diarrhetic shellfish poisoning, was identified by NMR spectroscopy using a chiral anisotropic reagent, phenylglycine methyl ester (PGME), which was condensed with a carboxyl group of 4.
M I Youshko et al.
Biochemistry. Biokhimiia, 65(12), 1367-1375 (2001-02-15)
Kinetic regularities of the enzymatic acyl group transfer reactions have been studied using ampicillin synthesis catalyzed by E. coli penicillin acylase as an example. It was shown that ampicillin synthesis proceeds through the formation of an acylenzyme-nucleophile complex capable of...
Esther M Gabor et al.
Protein engineering, design & selection : PEDS, 17(7), 571-579 (2004-08-31)
A semi-random mutagenesis approach was followed to increase the performance of penicillin acylase PAS2 in the kinetically controlled synthesis of ampicillin from 6-aminopenicillanic acid (6-APA) and activated D-phenylglycine derivatives. We directed changes in amino acid residues to positions close to...
P S Nys et al.
Antibiotiki, 26(12), 920-932 (1981-12-01)
The possible use of various procedures for estimation of the ionization constants of the Michaelis complex by the pH dependence of the maximum enzymatic reaction rate is discussed. It is shown that the procedures described in the literature for estimation...
Anna Serra et al.
Journal of environmental monitoring : JEM, 13(1), 167-174 (2010-11-17)
A comparative Life Cycle Assessment (LCA) of solar photo-Fenton and solar photoelectro-Fenton, two solar-driven advanced oxidation processes (AOPs) devoted to the removal of non-biodegradable pollutants in water, is performed. The study is based on the removal, at laboratory scale, of...

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