309923

Sigma-Aldrich

Ethyl nitrite solution

10-20 wt. % in ethanol

Linear Formula:
C2H5ONO
CAS Number:
Molecular Weight:
75.07
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

concentration

10-20 wt. % in ethanol

refractive index

n20/D 1.36

density

0.792 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CCON=O

InChI

1S/C2H5NO2/c1-2-5-3-4/h2H2,1H3

InChI key

QQZWEECEMNQSTG-UHFFFAOYSA-N

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General description

The reactions of ethyl nitrite solution with human haemoglobin and sperm whale myoglobin were studied.

Packaging

25 g in glass bottle

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

hazcat

Eye Irrit. 2 - Flam. Liq. 2

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 1

Flash Point(F)

59.0 °F - closed cup

Flash Point(C)

15 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

M P Doyle et al.
The Journal of biological chemistry, 256(23), 12399-12404 (1981-12-10)
The reactions of human hemoglobin and sperm whale myoglobin with ethyl nitrite under aerobic conditions have been examined in kinetic detail. Ethyl nitrite converts two equivalents of oxyhemoglobin or oxymyoglobin to their oxidized counterparts with concurrent production of one equivalent...
Kazufumi Shimazutsu et al.
Clinical and translational science, 2(6), 405-412 (2010-05-07)
A method to maintain organ blood flow during laparoscopic surgery has not been developed. Here we determined if ethyl nitrite, an S-nitrosylating agent that would maintain nitric oxide bioactivity (the major regulator of tissue perfusion), might be an effective intervention...
Richard L Auten et al.
American journal of respiratory and critical care medicine, 176(3), 291-299 (2007-05-05)
Inhaled nitric oxide (NO) has been used to prevent bronchopulmonary dysplasia, but with variable results. Ethyl nitrite (ENO) forms S-nitrosothiols more readily than does NO, and resists higher-order nitrogen oxide formation. Because S-nitrosylation is a key pathway mediating many NO...
Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
Steven H Abman et al.
Lancet (London, England), 360(9350), 2076-2077 (2002-12-31)
J C MacDonald et al.
Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 35(7), 485-487 (1981-01-01)
Gas chromatography--mass spectrometry demonstrates the presence of ethyl nitrite in the breath of volunteers subjects who smoke and drink concurrently. The mutagenic compound is quantitated at the ppb level by gas chromatography with the selective electron capture detector. The compound...

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