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324108

Sigma-Aldrich

Trimethylphosphine solution

1.0 M in THF, liquid

Synonym(s):

PMe3, Trimethylphosphorus

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100 ML
$226.00

$226.00


Estimated to ship onSeptember 04, 2025FromMILWAUKEE


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100 ML
$226.00

About This Item

Linear Formula:
(CH3)3P
CAS Number:
Molecular Weight:
76.08
Beilstein/REAXYS Number:
969138
MDL number:
UNSPSC Code:
12352128
PubChem Substance ID:
NACRES:
NA.22

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$226.00


Estimated to ship onSeptember 04, 2025FromMILWAUKEE


Request a Bulk Order
Technical Service
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Product Name

Trimethylphosphine solution, 1.0 M in THF

form

liquid

Quality Level

reaction suitability

reagent type: ligand
reaction type: Mitsunobu Reaction

reagent type: ligand
reaction type: Wittig Reaction

concentration

1.0 M in THF

density

0.872 g/mL at 25 °C

functional group

phosphine

SMILES string

CP(C)C

InChI

1S/C3H9P/c1-4(2)3/h1-3H3

InChI key

YWWDBCBWQNCYNR-UHFFFAOYSA-N

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This Item
324116245275323322
reaction suitability

reagent type: ligand
reaction type: Mitsunobu Reaction, reagent type: ligand
reaction type: Wittig Reaction

reaction suitability

reagent type: ligand
reaction type: Mitsunobu Reaction, reagent type: ligand
reaction type: Wittig Reaction

reaction suitability

reagent type: ligand
reaction type: Arylations

reaction suitability

-

form

liquid

form

liquid

form

liquid

form

liquid

functional group

phosphine

functional group

phosphine

functional group

phosphine

functional group

phosphine

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

density

0.872 g/mL at 25 °C

density

0.854 g/mL at 25 °C

density

0.802 g/mL at 20 °C (lit.)

density

0.738 g/mL at 20 °C (lit.)

concentration

1.0 M in THF

concentration

1.0 M in toluene

concentration

-

concentration

-

General description

Trimethylphosphine is the reagent used in Mitsunobu reaction. It participates in the transformation of azides into carbamates, aziridines from azidoalcohols, iminophosphoranes and aza-Wittig reaction. Electron diffraction study of trimethylphosphine has been reported.[1]

Application

Trimethylphosphine (PMe3) solution is the suitable reagent used in the synthesis of Fe/Te cluster type complex, Fe6Te8(PMe3)6.[2] It may be employed as a probe to investigate the acid sites in Y-zeolite.[3] It may be used for the synthesis of hexakis(trimethylphosphine)tris-μ-methylene-diruthenium(III).[4]

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

-22.0 °F - closed cup

flash_point_c

-30 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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