All Photos(1)

335754

Sigma-Aldrich

Pentaethylene glycol

98%

Synonym(s):
Pentaglycol, 3,6,9,12-Tetraoxatetradecane-1,14-diol
Linear Formula:
HO(CH2CH2O)5H
CAS Number:
Molecular Weight:
238.28
Beilstein:
1635593
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

98%

mol wt

average Mn 250

refractive index

n20/D 1.462 (lit.)

bp

184 °C/2 mmHg (lit.)

density

1.126 g/mL at 25 °C (lit.)

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

OCCOCCOCCOCCOCCO

InChI

1S/C10H22O6/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h11-12H,1-10H2

InChI key

JLFNLZLINWHATN-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Peng Shi et al.
Nature communications, 10(1), 2223-2223 (2019-05-22)
Mammalian cells are different from plant and microbial cells, having no exterior cell walls for protection. Environmental assaults can easily damage or destroy mammalian cells. Thus, the ability to develop a biomimetic cell wall (BCW) on their plasma membrane as...
Steven P D Harborne et al.
Scientific reports, 7, 45383-45383 (2017-03-30)
Mitochondrial ATP-Mg/Pi carriers import adenine nucleotides into the mitochondrial matrix and export phosphate to the cytosol. They are calcium-regulated to control the size of the matrix adenine nucleotide pool in response to cellular energetic demands. They consist of three domains:...
Alexis Hofherr et al.
PLoS biology, 16(8), e2005651-e2005651 (2018-08-07)
Cilia are organelles specialized in movement and signal transduction. The ciliary transient receptor potential ion channel polycystin-2 (TRPP2) controls elementary cilia-mediated physiological functions ranging from male fertility and kidney development to left-right patterning. However, the molecular components translating TRPP2 channel-mediated...
Stephany Jaiquel Baron et al.
Theranostics, 11(11), 5077-5091 (2021-04-17)
An increasing number of commonly prescribed drugs are known to interfere with mitochondrial function, causing cellular toxicity, but the underlying mechanisms are largely unknown. Although often not considered, mitochondrial transport proteins form a significant class of potential mitochondrial off-targets. So...
Chelsea L Price et al.
The journal of physical chemistry. A, 124(9), 1811-1820 (2020-02-06)
Single-particle trapping is an effective strategy to explore the physical and optical properties of aerosol with high precision. Laser-based methods are commonly used to probe the size, optical properties, and composition of nonlight-absorbing droplets in optical and electrodynamic traps. However...

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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