336467

Benz[cd]indol-2(1H)-one

technical grade

• Synonym(s): NSC 25094
• Empirical Formula (Hill Notation): C₁₁H₇NO
• CAS Number: 130-00-7
• Molecular Weight: 169.18
• EC Number: 204-973-4
• MDL number: MFCD00009748
• PubChem Substance ID: 24860382
• NACRES: NA.22

Properties

• grade: technical grade
• Quality Level: 100
• form: solid
• mp: 173-178 °C (lit.)
• solubility: methanol: soluble 25 mg/mL, clear to slightly hazy, yellow to brown
• SMILES string: O=C1Nc2cccc3cccc1c23
• InChI: 1S/C11H7NO/c13-11-8-5-1-3-7-4-2-6-9(12-11)10(7)8/h1-6H,(H,12,13)
• InChI key: GPYLCFQEKPUWLD-UHFFFAOYSA-N

Description

General description

Benz[cd]indol-2(1H)-one is also referred as naphtholactam.

Application

• Reactant in photo-Fries rearrangement
• Reactant in preparation of potential antitumor agents
• Reactant in synthesis of inhibitors of thymidylate synthase

Benz[cd]indol-2(1H)-one was used in the synthesis of 2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide analog, novel Mycobacterium protein tyrosine phosphatase B (mPTPB) inhibitor.

Packaging

5 g in glass bottle