All Photos(3)

337951

Sigma-Aldrich

Quercetin hydrate

≥95%

Empirical Formula (Hill Notation):
C15H10O7 · xH2O
CAS Number:
Molecular Weight:
302.24 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥95%

solubility

DMSO: soluble 200 mg/mL

SMILES string

[H]O[H].Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2

InChI key

OKXFBEYCJRMINR-UHFFFAOYSA-N

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General description

Quercetin is an antitrypanosomal and antileishmanial compound. Quercetin is a well-known bioflavonoid and its influence on tumour growth in vivo has been reported. Quercetic exhibits leishmanicidal effect on the amastigote stage of Leishmania donovani.

Application

Quercetin hydrate was used as leishmanicidal flavonol to investigate the inhibition of recombinant arginase from Leishmania amazonensis by quercetin, quercitrin and isoquercitrin.

Packaging

25, 100 g in poly bottle

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Shengfeng Peng et al.
Journal of agricultural and food chemistry, 67(26), 7506-7511 (2019-06-12)
The poor water solubility and oral bioavailability of many lipophilic polyphenols can be improved through the use of colloidal delivery systems. In this study, a pH-driven method was used to encapsulate curcumin, quercetin, and resveratrol within nanoliposomes. This method is...
Azar Kajbafvala et al.
Pharmaceutical development and technology, 23(8), 741-750 (2016-11-23)
The aim of this study was to develop a new microemulsion formulation for topical application of poorly soluble drug named quercetin. In order to design suitable microemulsion system, the pseudo-ternary phase diagrams of microemulsion systems were constructed at different surfactant/co-surfactant...
Hua Chen et al.
Food chemistry, 221, 248-257 (2016-12-17)
The study examined the capability of phytoglycogen (PG) to improve the water solubility of quercetin (QC). PG-QC formulations were prepared by mixing a QC ethanol solution with a PG aqueous solution followed with vacuum drying of the supernatant. PG-QC formulations...
Tumour response to quercetin, a bioflavonoid with some promises in therapies.
Indap MA, et al.
Indian Journal of Pharmaceutical Sciences, 68(5), 570-570 (2006)
Edson Roberto da Silva et al.
Experimental parasitology, 130(3), 183-188 (2012-02-14)
Polyamine biosynthesis enzymes are promising drug targets for the treatment of leishmaniasis, Chagas' disease and African sleeping sickness. Arginase, which is a metallohydrolase, is the first enzyme involved in polyamine biosynthesis and converts arginine into ornithine and urea. Ornithine is...

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