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341894

Sigma-Aldrich

Cyanogen bromide solution

3.0 M in methylene chloride

Linear Formula:
BrCN
CAS Number:
Molecular Weight:
105.92
Beilstein:
1697296
MDL number:
PubChem Substance ID:
NACRES:
NA.22

form

liquid

Quality Level

concentration

3.0 M in methylene chloride

solubility

alcohol: freely soluble
diethyl ether: freely soluble
water: freely soluble

density

1.443 g/mL at 25 °C

SMILES string

BrC#N

InChI

1S/CBrN/c2-1-3

InChI key

ATDGTVJJHBUTRL-UHFFFAOYSA-N

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General description

Cyanogen bromide solution induces template-guided condensation of oligonucleotides only in the presence of N-substituted morpholines.Mechanism of the phosphomonoester group activation by cyanogen bromide in N-substituted morpholine buffers is investigated.

Application

Cyanogen bromide (CNBr) solution may be used in the cyanogen bromide method for covalent immobilization of trypsin onto poly(2-hydroxyethyl methacrylate)/ polystyrene composite microspheres. It may be used in the preparation of CNBr-activated diol-silica, useful as silica support in HPLC.

Packaging

100 mL in glass bottle

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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