341894

Cyanogen bromide solution

3.0 M in methylene chloride

• Linear Formula: BrCN
• CAS Number: 506-68-3
• Molecular Weight: 105.92
• Beilstein: 1697296
• MDL number: MFCD00011597
• PubChem Substance ID: 24861007
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• concentration: 3.0 M in methylene chloride
• solubility: alcohol: freely soluble; diethyl ether: freely soluble; water: freely soluble
• density: 1.443 g/mL at 25 °C
• SMILES string: BrC#N
• InChI: 1S/CBrN/c2-1-3
• InChI key: ATDGTVJJHBUTRL-UHFFFAOYSA-N

Description

General description

Cyanogen bromide solution induces template-guided condensation of oligonucleotides only in the presence of N-substituted morpholines.Mechanism of the phosphomonoester group activation by cyanogen bromide in N-substituted morpholine buffers is investigated.

Application

Cyanogen bromide (CNBr) solution may be used in the cyanogen bromide method for covalent immobilization of trypsin onto poly(2-hydroxyethyl methacrylate)/ polystyrene composite microspheres. It may be used in the preparation of CNBr-activated diol-silica, useful as silica support in HPLC.

Packaging

100 mL in glass bottle

Safety Information

• Pictograms: GHS05,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H300 + H330 - H311 - H314 - H336 - H351
• Precautionary Statements: P201 - P280 - P301 + P310 + P330 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Central nervous system
• Supplementary Hazards: EUH032
• Storage Class Code: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves