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344249

Sigma-Aldrich

Diphenyl phosphoryl chloride

96%

Synonym(s):
Diphenyl chlorophosphate, Diphenyl phosphorochloridate
Linear Formula:
(C6H5O)2POCl
CAS Number:
Molecular Weight:
268.63
Beilstein:
654130
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

10 mmHg ( 190 °C)

Assay

96%

form

liquid

refractive index

n20/D 1.55 (lit.)

bp

314-316 °C/272 mmHg (lit.)

density

1.296 g/mL at 25 °C (lit.)

SMILES string

ClP(=O)(Oc1ccccc1)Oc2ccccc2

InChI

1S/C12H10ClO3P/c13-17(14,15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H

Inchi Key

BHIIGRBMZRSDRI-UHFFFAOYSA-N

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1 of 4

This Item
D206555377015C39288
form

liquid

form

liquid

form

-

form

powder

refractive index

n20/D 1.55 (lit.)

refractive index

n20/D 1.55 (lit.)

refractive index

-

refractive index

-

bp

314-316 °C/272 mmHg (lit.)

bp

314-316 °C/272 mmHg (lit.)

bp

-

bp

193 °C/27 mmHg (lit.)

density

1.296 g/mL at 25 °C (lit.)

density

1.296 g/mL at 25 °C (lit.)

density

-

density

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

General description

Diphenyl phosphoryl chloride is a diaryl phosphoryl derivative. It is formed during the preparation of monophenyl phosphoryl chloride via reaction of phenol and phosphorus oxychloride.

Application

Diphenyl phosphoryl chloride may be used:
  • in the preparation of guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphate
  • as phosphorylating agent for the synthesis of 2-deoxy-D-galactose-3 and -6 phosphoric acids
  • in the synthesis of diaryl phosphoryl derivatives of alkylene dithiophosphates

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Customers Also Viewed

Synthesis of Disodium Phenyl Phosphate.
Freeman HF and Colver CW.
Journal of the American Chemical Society, 60(4), 750-751 (1938)
Dialkyl (aryl) phosphoryl derivatives of alkylene dithiophosphates.
Sharma CS and Nagar PN.
Phosphorus, Sulfur, and Silicon and the Related Elements, 179(9), 1793-1798 (2004)
Y Furuichi et al.
The Journal of biological chemistry, 251(16), 5043-5053 (1976-08-25)
Blocked and methylated 5' termini of reovirus mRNA are formed by viral cores at an early stage of transcription. Cores incubated in a complete transcription reaction mixture for 30 s, or in a mixture lacking UTP and ATP for a
219. Deoxy-sugars. Part XV. D-Galactose-3 and-6 phosphoric acids and their 2-deoxy-analogues.
Foster AB, et al.
Journal of the Chemical Society, 980-987 (1951)

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