Skip to Content
MilliporeSigma
All Photos(3)

Documents

344249

Sigma-Aldrich

Diphenyl phosphoryl chloride

96%

Synonym(s):

Diphenyl chlorophosphate, Diphenyl phosphorochloridate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(C6H5O)2POCl
CAS Number:
Molecular Weight:
268.63
Beilstein/REAXYS Number:
654130
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

10 mmHg ( 190 °C)

Quality Level

assay

96%

form

liquid

refractive index

n20/D 1.55 (lit.)

bp

314-316 °C/272 mmHg (lit.)

density

1.296 g/mL at 25 °C (lit.)

SMILES string

ClP(=O)(Oc1ccccc1)Oc2ccccc2

InChI

1S/C12H10ClO3P/c13-17(14,15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H

InChI key

BHIIGRBMZRSDRI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Diphenyl phosphoryl chloride is a diaryl phosphoryl derivative. It is formed during the preparation of monophenyl phosphoryl chloride via reaction of phenol and phosphorus oxychloride.

Application

Diphenyl phosphoryl chloride may be used:
  • in the preparation of guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphate
  • as phosphorylating agent for the synthesis of 2-deoxy-D-galactose-3 and -6 phosphoric acids
  • in the synthesis of diaryl phosphoryl derivatives of alkylene dithiophosphates

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dialkyl (aryl) phosphoryl derivatives of alkylene dithiophosphates.
Sharma CS and Nagar PN.
Phosphorus, Sulfur, and Silicon and the Related Elements, 179(9), 1793-1798 (2004)
219. Deoxy-sugars. Part XV. D-Galactose-3 and-6 phosphoric acids and their 2-deoxy-analogues.
Foster AB, et al.
Journal of the Chemical Society, 980-987 (1951)
Synthesis of Disodium Phenyl Phosphate.
Freeman HF and Colver CW.
Journal of the American Chemical Society, 60(4), 750-751 (1938)
Y Furuichi et al.
The Journal of biological chemistry, 251(16), 5043-5053 (1976-08-25)
Blocked and methylated 5' termini of reovirus mRNA are formed by viral cores at an early stage of transcription. Cores incubated in a complete transcription reaction mixture for 30 s, or in a mixture lacking UTP and ATP for a

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service