345059

Sigma-Aldrich

4-Fluoro-2-nitrophenol

99%

Linear Formula:
FC6H3(NO2)OH
CAS Number:
Molecular Weight:
157.10
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

99%

mp

75-77 °C (lit.)

SMILES string

Oc1ccc(F)cc1N+(O-)=O

InChI

1S/C6H4FNO3/c7-4-1-2-6(9)5(3-4)8(10)11/h1-3,9H

InChI key

ZHRLVDHMIJDWSS-UHFFFAOYSA-N

General description

4-Fluoro-2-nitrophenol is formed during iron(III) nitrate nonahydrate activated by tungstophosphoric acid cesium salt catalyzed nitration of 4-fluorophenol.

Application

4-Fluoro-2-nitrophenol may be used in the preparation of 5-fluoro-2-methoxyanilineand 5-fluoro-2-hydroxyaniline.

Packaging

5, 25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

20/21/22-36/37/38

Safety Statement

26-36

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Catalytic effects of some Keggin-type heteropoly acids and polyoxometalates on selective nitration of phenols.
Amani K and Maleki F.
Journal of the Iranian Chemical Society, 4(2), 238-243 (2007)
I M Rietjens et al.
European journal of biochemistry, 194(3), 945-954 (1990-12-27)
Pathways for biodehalogenation of fluorinated aniline derivatives were investigated. Microsomal NADPH-dependent dehalogenation of fluoroanilines was shown to proceed by three different reaction pathways. The first route appeared to result in monooxygenation at a fluorinated position and release of the fluorine...
SOME SYNTHESES FROM p-FLUOROANISOLE.
BUU-HOI NP, et al.
The Journal of Organic Chemistry, 19(10), 1617-1621 (1954)
J I Cacho et al.
Journal of chromatography. A, 1456, 27-33 (2016-06-19)
A rapid and sensitive procedure for the determination of six NPs in soils by gas chromatography and mass spectrometry (GC-MS) is proposed. Ultrasound assisted extraction (UAE) is used for NP extraction from soil matrices to an organic solvent, while the...
Marta Pastor-Belda et al.
Talanta, 189, 543-549 (2018-08-09)
This paper presents a procedure for the determination of seven nitrophenols (NPs) in water and soil samples using stir bar sorptive extraction (SBSE) coupled to gas chromatography with mass spectrometry (GC-MS) by means of a thermal desorption unit (TDU). Microwave...

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