346292

Sigma-Aldrich

4,4-Dimethyl-2-phenyl-2-oxazoline

96%

Empirical Formula (Hill Notation):
C11H13NO
CAS Number:
Molecular Weight:
175.23
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

96%

refractive index

n20/D 1.5322 (lit.)

bp

124 °C/20 mmHg (lit.)

mp

20-24 °C (lit.)

density

1.025 g/mL at 25 °C (lit.)

SMILES string

CC1(C)COC(=N1)c2ccccc2

InChI

1S/C11H13NO/c1-11(2)8-13-10(12-11)9-6-4-3-5-7-9/h3-7H,8H2,1-2H3

InChI key

UGNSMKDDFAUGFT-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4,4-Dimethyl-2-phenyl-2-oxazoline is an 2-aryl-2-oxazoline and has been tested as as ligand for the Suzuki coupling reaction of aryl bromides and arylboronic acids. 4,4-Dimethyl-2-phenyl-2-oxazoline forms mildly hygroscopic complexes, of general formulae ZnX2(ox)2 (ox =4,4-Dimethyl-2-phenyl-2-oxazoline), with ether solutions of ZnX2 (X = Cl, Br, I).Except ZnI2, which does not form an isolable complex due to steric reasons.

Application

4,4-Dimethyl-2-phenyl-2-oxazoline may be used in the synthesis of an ester-ammonium salt via rupture of oxazoline ring.

Packaging

10, 50 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

217.4 °F - closed cup

Flash Point(C)

103 °C - closed cup

Oxazoline chemistry-Part IV: Synthesis and characterization of oxazoline complexes of the zinc halides.
Barclay TM, et al.
Canadian Journal of Chemistry, 81(12), 1482-1491 (2003)
Oxazoles XXI. Three Ester Ammonium Salts Resulting from the Rupture of an Oxazoline Ring.
Gossage RA, et al.
Journal of Chemical Crystallography, 40(3), 272-277 (2010)
Pd (OAc)2/2-aryl-2-oxazolines catalyzed Suzuki coupling reactions of aryl bromides and arylboronic acids.
Tao B and Boykin DW.
Tetrahedron Letters, 43(28), 4955-4957 (2002)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.