346683

Sigma-Aldrich

2-Phenoxyaniline

99%

Synonym(s):
2-Aminophenyl phenyl ether
Linear Formula:
C6H5OC6H4NH2
CAS Number:
Molecular Weight:
185.22
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

99%

bp

170 °C/18 mmHg (lit.)

mp

47-49 °C (lit.)

SMILES string

Nc1ccccc1Oc2ccccc2

InChI

1S/C12H11NO/c13-11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9H,13H2

InChI key

NMFFUUFPJJOWHK-UHFFFAOYSA-N

Related Categories

General description

2-Phenoxyaniline forms crystalline 2:1 (host-to-guest) inclusion complexes with β-cyclodextrin.

Application

2-Phenoxyaniline may be used in the preparation of sodium primary amide complex, 2-PhOC6H4NHNa·NMe(CH2)2NMe22. It was used in the preparation of 2-acetoaminodiphenyl ether. It may be used in the preparation of 4-methyl-2-(2-phenoxyphenyl)azo-phenol.

Packaging

25, 500 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

20/21/22-36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Susana S Braga et al.
Organic & biomolecular chemistry, 1(5), 873-878 (2003-08-22)
Crystalline 1:1 inclusion complexes with beta-cyclodextrin (beta-CD) and the sodium salt of nimesulide (4-nitro-2-phenoxymethanesulfonanilide), and the sodium salt of the derivative 2-phenoxymethanesulfonanilide, have been prepared by co-precipitation from aqueous solution. The presence of true inclusion complexes was supported by elemental...
Ferenc Szurdoki et al.
Journal of agricultural and food chemistry, 50(1), 29-40 (2002-01-05)
Sensitive and selective enzyme-linked immunosorbent assays (ELISAs) in the immobilized antigen format were developed for fenoxycarb (1), an insect growth regulator (IGR). The parent molecule [ethyl 2-(4-phenoxyphenoxy)ethylcarbamate] was derivatized at several positions to obtain haptens (2-5) that were used to...
The first structurally characterised sodium primary amide complex; synthesis and crystal structure of 2-PhOC6H4NHNa? NMe [(CH2) 2NMe2] 2.
Cragg-Hine I, et al.
J. Chem. Soc., Dalton Trans., 19, 2901-2902 (1994)
Synthesis and Pharmacological Evaluation of Certain Schiff Bases and Thiazoldine derivatives as AT1 angiotension-II (AII) receptor antagonists.
Shreenivas MT, et al.
Journal of Pharmaceutical Science and Technology, 1(2), 88-94 (2009)

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