348015

2-Aminobenzylamine

98%

• Synonym(s): (2-Aminomethylphenyl)amine, 2-(Aminomethyl)aniline, 2-(Aminomethyl)benzenamine, 2-Amino-1-benzylamine, [(2-Aminophenyl)methyl]amine, o-Aminobenzylamine
• Linear Formula: H₂NC₆H₄CH₂NH₂
• CAS Number: 4403-69-4
• Molecular Weight: 122.17
• NACRES: NA.22
• PubChem Substance ID: 24861542
• UNSPSC Code: 12352100
• MDL number: MFCD00075408
• Assay: 98%
• Form: solid

Properties

• Quality Segment: 100
• assay: 98%
• form: solid
• mp: 58-61 °C (lit.)
• functional group: amine
• SMILES string: NCc1ccccc1N
• InChI: 1S/C7H10N2/c8-5-6-3-1-2-4-7(6)9/h1-4H,5,8-9H2
• InChI key: GVOYKJPMUUJXBS-UHFFFAOYSA-N

Description

General description

2-Aminobenzylamine undergoes three-component cyclisation reactions with methyl 3,3,3-trifluoropyruvate, 2-aminobenzylamine and oxo compounds to afford regio- and stereoisomers of tetrahydropyrroloquinazolinones.[1]

Application

2-Aminobenzylamine may be used:

• in the synthesis of 1,2,3,4-tetrahydroquinazoline oxime, via condensation reaction with 2-(naphthalen-2-yl)-2-oxoacetaldehyde oxime[2]
• in the synthesis of alkyl 5H-1,4-benzodiazepine-3-carboxylates[3]
• to modify the phosphate groups on phosphoserine peptides[4]

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges