348074

Sigma-Aldrich

2-Chloro-4-fluorobenzaldehyde

97%

Linear Formula:
ClC6H3(F)CHO
CAS Number:
Molecular Weight:
158.56
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

bp

118-120 °C/50 mmHg (lit.)

mp

60-63 °C (lit.)

SMILES string

Fc1ccc(C=O)c(Cl)c1

InChI

1S/C7H4ClFO/c8-7-3-6(9)2-1-5(7)4-10/h1-4H

InChI key

KMQWNQKESAHDKD-UHFFFAOYSA-N

General description

2-Chloro-4-fluorobenzaldehyde is a halogen substituted benzaldehyde.

Application

2-Chloro-4-fluorobenzaldehyde may be used in the synthesis of substituted α-cyanocinnamic acid, via Knoevenagel condensation reaction. It may be used in the synthesis of 2-(2-benzimidazolyl)-3-(2-chloro-4-fluorophenyl)acrylonitrile.

Packaging

1, 5 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Biological activity and DNA binding studies of 2-substituted benzimidazo [1, 2-a] quinolines bearing different amino side chains.
Perin N, et al.
MedChemComm, 4(12), 1537-1550 (2013)
Thorsten W Jaskolla et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(34), 12200-12205 (2008-08-30)
Matrix-assisted laser desorption ionization (MALDI) has become an enabling technology for the fields of protein mass spectrometry (MS) and proteomics. Despite its widespread use, for example, in protein identification via peptide mass fingerprinting, a comprehensive model for the generation of...
Articles
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
Read More

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