W Kuźmierkiewicz et al.
Die Pharmazie, 40(7), 462-464 (1985-07-01)
Condensation reactions of 3-(1H-benzimidazole-2)propanoic acid (procodazol) with aromatic aldehydes were carried out resulting in lactam and acid derivatives. Basing on the spectral studies (MS, NMR) it was found that in the reaction the hydrogen atoms of the 3-methylene group of...
Christine M Crane et al.
ChemMedChem, 3(1), 91-101 (2007-11-23)
The enzymes of the non-mevalonate pathway for isoprenoid biosynthesis are attractive targets for the development of novel drugs against malaria and tuberculosis. This pathway is used exclusively by the corresponding pathogens, but not by humans. A series of water-soluble, cytidine-based...
Ghassan Abu Sheikha et al.
Chemical & pharmaceutical bulletin, 66(4), 423-426 (2018-04-03)
Hyperlipidemia is known as an elevation of plasma lipid components. It contributes significantly to atherosclerosis which is one of the most important causative factors in cardiovascular diseases. Agents that cause a dramatic decrease in serum lipid levels are of great...
E Moran et al.
Journal of immunological methods, 271(1-2), 65-75 (2002-11-26)
Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans...
A Potentiometric Study of 2-Substituted Benzimidazole Ligands1.
Lane TJ and Daly JM.
Journal of the American Chemical Society, 81(12), 2953-2955 (1959)