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362425

Sigma-Aldrich

2-Chloro-N-methoxy-N-methylacetamide

98%

Linear Formula:
ClCH2CON(OCH3)CH3
CAS Number:
Molecular Weight:
137.56
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

solid

mp

39-41 °C (lit.)

storage temp.

2-8°C

SMILES string

CON(C)C(=O)CCl

InChI

1S/C4H8ClNO2/c1-6(8-2)4(7)3-5/h3H2,1-2H3

InChI key

SCOJKGRNQDKFRP-UHFFFAOYSA-N

Related Categories

General description

2-Chloro-N-methoxy-N-methylacetamide is a Weinreb amide.

Application

2-Chloro-N-methoxy-N-methylacetamide may be used in the preparation of:
  • 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS) and structurally related 2-alkyl-4-quinolones having biological activity
  • 2-(benzo[d]thiazol-2-ylsulfonyl)-N-methoxy-N-methylacetamide
  • α-chloro-ketone, starting reagent for the one-pot synthesis of 2-heptyl-3-hydroxyl-4(1H)-quinolone (PQS), signalling molecule in the quorum sensing of Pseudomonas aeruginosa

Packaging

5, 25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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