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363081

Poly(vinyl alcohol)

average Mw 85,000-124,000, 87-89% hydrolyzed

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Pack SizeSKUAvailabilityPrice
25 g

Available to ship TODAYfromMILWAUKEE

$55.90
500 g

Available to ship TODAYfromMILWAUKEE

$161.00
1 kg

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$259.00

About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
NACRES:
NA.23
UNSPSC Code:
12352104
MDL number:
MFCD00081922

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Quality Level

200

form

powder or crystals

mol wt

average Mw 85,000-124,000

falling ball

23-27 cP, 4 % in H2O(20 °C)(lit.)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

General description

Polyvinyl alcohol(PVA) is a linear hydrophilic synthetic polymer with a backbone composed of only carbon atoms. Due to its inertness and stability, it is considered safe and biocompatible. It is also biodegradable under both anaerobic and aerobic conditions. Owing to its unique properties such as adhesiveness, safety, strength, film-forming, swelling, and non-carcinogenicity, it is widely used in paper, adhesives,food, biomedical and pharmaceutical industries. The partially hydrolyzed PVA(87–89%) is more soluble in water and it has more flexibility and adhesion tohydrophobic surfaces.

Application

PVA has remarkable properties for a polymer to be used in drug delivery systems such as high surface stabilization, and low protein adsorption. The use of PVA in solid dispersion prevents crystal formation and improves the solubility of drugs. It can also be used as a granulating liquid to prevent slow crystal growth and nucleation. In conjunction with its copolymers, it can be useful for both hydrophilic and hydrophobic drugs. PVA hydrogels and microparticles can be used in drug delivery systems for cancer drugs.

PVA can be used as a surface stabilizer in preparing drug delivery carriers for the slow release of tetracycline.

Highly concentrated alginate/polyvinyl alcohol (PVA) bioinks can be used to prepare 3D bioprinting porous scaffolds. Partial diffusion of PVA sols from printed scaffolds creates a large number of micropores.

PVA can also be used as a water-soluble polymer template to synthesize nanosized polypyrrole via in situ polymerization. PVA generates stable dispersions of polypyrrole nanospheres in water and the size of nanospheres depends on the molecular weight and concentration of PVA.

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This Item
363103563900363065
Poly(vinyl alcohol) average Mw 85,000-124,000, 87-89% hydrolyzed

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363081

Poly(vinyl alcohol)

Poly(vinyl alcohol) average Mw 146,000-186,000, 87-89% hydrolyzed

Sigma-Aldrich

363103

Poly(vinyl alcohol)

Poly(vinyl alcohol) average Mw 130,000, 99+% hydrolyzed

Sigma-Aldrich

563900

Poly(vinyl alcohol)

Poly(vinyl alcohol) Mw 150,000 (average), 99+% hydrolyzed

Sigma-Aldrich

363065

Poly(vinyl alcohol)

form

powder or crystals

form

powder or crystals

form

powder or crystals

form

crystalline powder, crystals

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

mol wt

average Mw 85,000-124,000

mol wt

average Mw 146,000-186,000

mol wt

average Mw 130,000

mol wt

Mw 150,000 (average)

falling ball

23-27 cP, 4 % in H2O(20 °C)(lit.)

falling ball

40-50 cP, 4 % in H2O(20 °C)(lit.)

falling ball

56-68 cP, 4 % in H2O(20 °C)(lit.)

falling ball

55-65 cP, 4 % in H2O(20 °C)(lit.)

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB6691
MKDB4478
MKCX9886
MKCX8973
MKCX4558

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Chihiro Fujiyabu et al.
Scientific reports, 9(1), 10653-10653 (2019-07-25)
Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost
Gabriela Rivera-Hernández et al.
International journal of pharmaceutics, 600, 120478-120478 (2021-03-17)
Polyvinyl alcohol (PVA) is a biodegradable semicrystalline synthetic polymer that has been used for biomedical applications for several years. In the pharmaceutical area, PVA has been widely used to prepare solid dispersions to improve the solubility of drugs. Furthermore, it
Adam C Wilkinson et al.
Nature, 571(7763), 117-121 (2019-05-31)
Multipotent self-renewing haematopoietic stem cells (HSCs) regenerate the adult blood system after transplantation1, which is a curative therapy for numerous diseases including immunodeficiencies and leukaemias2. Although substantial effort has been applied to identifying HSC maintenance factors through the characterization of
View All Related Papers

Global Trade Item Number

SKUGTIN
363081-25G04061831824995
363081-1KG04061831824988
363081-500G04061831825008

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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