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363502

Sigma-Aldrich

Poly[(R)-3-hydroxybutyric acid]

natural origin

Synonym(s):
PHB, (R)-3-Hydroxybutyric acid polymerized
Linear Formula:
[COCH2CH(CH3)O]n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

transition temp

Tm 172 °C (DSC)

SMILES string

CC(O)CC(O)=O

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General description

Biocompatible, biodegradable polymer.

Application

Poly[(R)-3-hydroxybutyric acid (PHB) is a biodegradable and biocompatible polymer produced by several bacterial species, owing to its low resorbability and tunable properties, it may find uses in a variety of applications such as tissue engineering, controlled release systems etc.

Packaging

10, 100 g in poly bottle

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Molecular mass of poly [(R)-3-hydroxybutyric acid] produced in a recombinant Escherichia coli.
Kusaka S, et al.
Applied Microbiology and Biotechnology, 47(2), 140-143 (1997)
Proliferation and skeletal myotube formation capability of C2C12 and H9c2 cells on isotropic and anisotropic electrospun nanofibrous PHB scaffolds.
Ricotti L, et al.
Biomedical Materials (Bristol, England), 7(3), 035010-035010 (2012)
Engineering of Saccharomyces cerevisiae for the production of poly-3-d-hydroxybutyrate from xylose.
Sandstrom A G, et al.
AMB Express, 5(1), 14-14 (2015)
Andreas Wahl et al.
BMC microbiology, 12, 262-262 (2012-11-20)
Poly(3-hydroxybutyrate) (PHB) granules are important storage compounds of carbon and energy in many prokaryotes which allow survival of the cells in the absence of suitable carbon sources. Formation and subcellular localization of PHB granules was previously assumed to occur randomly
Daniel Pfeiffer et al.
Journal of bacteriology, 194(21), 5909-5921 (2012-08-28)
Poly(3-hydroxybutyrate) (PHB) granules are covered by a surface layer consisting of mainly phasins and other PHB granule-associated proteins (PGAPs). Phasins are small amphiphilic proteins that determine the number and size of accumulated PHB granules. Five phasin proteins (PhaP1 to PhaP5)

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