365823

Sigma-Aldrich

2-Fluoro-5-nitrobenzotrifluoride

98%

Synonym(s):
5-Nitro-α,α,α,2-tetrafluorotoluene
Linear Formula:
FC6H3(NO2)CF3
CAS Number:
Molecular Weight:
209.10
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

98%

refractive index

n20/D 1.465 (lit.)

bp

105-110 °C/25 mmHg (lit.)

density

1.522 g/mL at 25 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(F)c(c1)C(F)(F)F

InChI

1S/C7H3F4NO2/c8-6-2-1-4(12(13)14)3-5(6)7(9,10)11/h1-3H

InChI key

DNTHMWUMRGOJRY-UHFFFAOYSA-N

General description

2-Fluoro-5-nitrobenzotrifluoride is formed during the fluorodenitration of 2-(4-chlorobenzene sulfonyl)-5-nitrotrifluoride using tetramethyl ammonium fluoride.

Application

2-Fluoro-5-nitrobenzotrifluoride may be used in the synthesis of [3-(4-nitro-2-trifluoromethylphenyl)aminophenyl]dihydroxyborane.

Packaging

5, 25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

WGK Germany

WGK 3

Flash Point(F)

197.6 °F - closed cup

Flash Point(C)

92 °C - closed cup

Isomerisation accompanying fluorodenitration of trifluoromethyl activated diphenyl sulfones.
Clark JH and Wails D.
Tetrahedron Letters, 34(24), 3901-3902 (1993)
Tatsuya Higashi et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(12), 1301-1307 (2002-12-28)
Derivatization of neutral steroids for increasing sensitivity in liquid chromatography/negative atmospheric pressure chemical ionization-mass spectrometry (APCI-MS) has been examined. Under APCI conditions, gas-phase electrons are provided by the corona discharge and captured by electron-affinitive compounds. In negative APCI-MS, therefore, ultrahigh...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.