4,4′-Methylenebis(2-methylcyclohexylamine), mixture of isomers


Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
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PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level



refractive index

n20/D 1.499 (lit.)


93-100 °C (lit.)


0.94 g/mL at 25 °C (lit.)

SMILES string




InChI key


Related Categories

General description

4,4′-Methylenebis(2-methylcyclohexylamine) is an alicyclic diamine.


4,4′-Methylenebis(2-methylcyclohexylamine) (MMCA) may be used:
  • in the synthesis of fully aliphatic polyimides
  • in the synthesis of fully aliphatic polyimide-siloxanes (APISiO)
  • to prepare epoxy resin with trimethylolpropane triglycidyl ether, used for the characterization of the structural organization in dragline silk by transmission X-ray microscopy (STXM).


1 L in glass bottle
250 mL in glass bottle

Signal Word


Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


UN2927 - class 6.1 - PG 2 - EHS - basic - Toxic liquids, corrosive, organic, n.o.s., HI: all

WGK Germany


Flash Point(F)

343.4 °F - closed cup

Flash Point(C)

173 °C - closed cup

S Ohshima et al.
The Journal of toxicological sciences, 11(2), 79-93 (1986-05-01)
Amine-curing agent for epoxy resin, bis(4-amino-3-methyl-cyclohexyl)methane (commercial name; Laromin C) has been suspected to have induced in the workers some toxic signs such as collagen disease like scleroderma or polymyositis. Subacute toxicity of this agent was studied in rats following...
H Ishikawa et al.
Dermatologica, 161(3), 145-151 (1980-01-01)
The presence of sclerosis-inducing glycosaminoglycan in the skin was confirmed in an experimental skin sclerosis induced by a chemical compound. An experimental skin sclerosis was first produced in the mouse with bis(4-amino-3-methylcyclohexyl)methane. Out of glycosaminoglycans isolated from the slightly changed...
S Ohshima et al.
Sangyo igaku. Japanese journal of industrial health, 26(3), 197-204 (1984-05-01)
Amine-curing agent for epoxy resin, bis(4-amino-3-methylcyclohexyl)methane, has been suspected of inducing toxic symptoms in man which resemble collagen disease such as scleroderma or polymyositis. We studied subacute toxicity of this agent by repeated oral administrations to rats. The agent was...
Synthesis and characterization of novel fully aliphatic polyimidosiloxanes based on alicyclic or adamantyl diamines.
Mathews AS, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 44(18), 5254-5270 (2006)
Fully aliphatic polyimides from adamantane-based diamines for enhanced thermal stability, solubility, transparency, and low dielectric constant.
Mathews AS, et al.
Journal of Applied Polymer Science, 102(4), 3316-3326 (2006)

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