371777

Sigma-Aldrich

N-(4-Aminophenyl)-4-methylbenzenesulfonamide

99%

Linear Formula:
CH3C6H4SO2NHC6H4NH2
CAS Number:
Molecular Weight:
262.33
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

99%

mp

183-185 °C (lit.)

SMILES string

Cc1ccc(cc1)S(=O)(=O)Nc2ccc(N)cc2

InChI

1S/C13H14N2O2S/c1-10-2-8-13(9-3-10)18(16,17)15-12-6-4-11(14)5-7-12/h2-9,15H,14H2,1H3

InChI key

XKDFMOOUKPSLEM-UHFFFAOYSA-N

General description

N-(4-Aminophenyl)-4-methylbenzenesulfonamide is a sulfonamide derivative. It has been reported to crystallize in an asymmetric unit containing two independent molecules, having V-shaped conformations. Its crystals are orthorhombic having space group P212121.

Application

N-(4-Aminophenyl)-4-methylbenzenesulfonamide may be used in the preparation of following compounds:
  • 4-methyl-N-4-3-(2-naphthyl)imidazo1,2-apyrazine-8-ylaminophenylbenzenesulfonamide
  • 4-methyl-N-4-2-(2-naphthyl)imidazo1,2-apyrazine-8-ylaminophenylbenzenesulfonamide
  • 2- and 3-substituted 8-amino imidazo1,2-apyrazines

Packaging

1 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

James R Sayer et al.
Bioorganic & medicinal chemistry, 22(22), 6459-6470 (2014-12-03)
A novel series of 8-amino imidazo[1,2-a]pyrazine derivatives has been developed as inhibitors of the VirB11 ATPase HP0525, a key component of the bacterial type IV secretion system. A flexible synthetic route to both 2- and 3-aryl substituted regioisomers has been...
Jeveria Rehman et al.
Acta crystallographica. Section E, Structure reports online, 67(Pt 10), o2709-o2709 (2011-11-09)
The title compound, C(13)H(14)N(2)O(2)S, crystallized with two independent mol-ecules in the asymmetric unit. They both have V-shaped conformations: the dihedral angles between their benzene rings are identical [45.86 (13)°] and their C-S-N-C torsion angles are similar [67.9 (3) and 70.2 (3)°]. In the...

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