375195

Sigma-Aldrich

Trimethyltin chloride solution

1.0 M in THF

Linear Formula:
(CH3)3SnCl
CAS Number:
Molecular Weight:
199.27
Beilstein/REAXYS Number:
3535111
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

concentration

1.0 M in THF

density

0.988 g/mL at 25 °C

SMILES string

CSn(C)(C)Cl

InChI

1S/3CH3.ClH.Sn/h3*1H3;1H;/q;;;;+1/p-1

InChI key

KWTSZCJMWHGPOS-UHFFFAOYSA-M

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Packaging

4×25, 100 mL in Sure/Seal™
The 25 mL Sure/Seal bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Target Organs

Respiratory system

Supp Hazards

EUH018 - EUH019

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

F,T+,N

Risk Statement

11-19-26/27/28-36/37/38-40-48/23/25-50/53

Safety Statement

16-26-28-36/37-45-61

RIDADR

UN 1992 6.1(3) / PGI

WGK Germany

WGK 2

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17 °C - closed cup

Katharina Krüger et al.
British journal of pharmacology, 144(2), 283-292 (2005-01-19)
1. Organotin compounds such as trimethyltin chloride (TMT) are among the most toxic of the organometallics. As their main target for toxicity is the central nervous system, the aim of the present study was to investigate the effects of TMT...
Kiyokazu Ogita et al.
Journal of neuroscience research, 82(5), 609-621 (2005-11-08)
The hippocampal dentate gyrus in adult animals is known to contain neural progenitors that proliferate and differentiate into neurons in response to brain injury. Little has been observed, however, on regeneration of the granule cell layer of the dentate gyrus...
Makoto Shuto et al.
Journal of pharmacological sciences, 110(4), 424-436 (2009-07-16)
The organotin trimethyltin (TMT) is known to cause neuronal degeneration in the murine brain. Earlier studies indicate that TMT-induced neuronal degeneration is enhanced by adrenalectomy. However, no evaluation has been attempted to determine the mechanism underlying the enhancement of TMT...
Alessandra Tamburella et al.
European journal of pharmacology, 683(1-3), 148-154 (2012-03-20)
This study was carried out to assess the behavioral effects of the non-psychostimulant drug atomoxetine, in rats prenatally-exposed to the organic compound trimethyltin chloride (TMT) and in spontaneously hypertensive rat (SHR), two rodent models of Attention Deficit/Hyperactivity Disorder (ADHD). At...
Koichi Kawada et al.
Journal of neuroscience research, 86(7), 1635-1646 (2008-01-10)
Our earlier study demonstrated that in vivo acute treatment with trimethyltin chloride (TMT) produces severe neuronal damage in the dentate gyrus and cognition impairment in mice. In the present study, we assessed whether TMT was capable of causing neuronal degeneration...

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