376876

N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide

98%

• Synonym(s): (N-Methoxymethylaminocarbonylmethylene)triphenylphosphorane
• Linear Formula: (C₆H₅)₃P=CHCON(OCH₃)CH₃
• CAS Number: 129986-67-0
• Molecular Weight: 363.39
• Beilstein/REAXYS Number: 4198472
• MDL number: MFCD00134433
• UNSPSC Code: 12352002
• PubChem Substance ID: 24863472
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 98%
• reaction suitability: reaction type: C-C Bond Formation
• mp: 173-175 °C (lit.)
• functional group: amine; phosphine
• SMILES string: CON(C)C(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H22NO2P/c1-23(25-2)22(24)18-26(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3
• InChI key: DGBLSOOPDBHHRX-UHFFFAOYSA-N

Description

Application

Reactant for:

• Synthesis of electron-deficient alkenes via stereoselective olefination of N-sulfonyl imines
• Phosphine-catalyzed asymmetric addition reactions
• Cysteine-catalyzed enantioselective intramolecular Rauhut-Currier reaction
• Wittig olefination
• Synthesis of aigialomycin D, a Protein Kinase inhibitor and a potential anticancer agent

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves