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379506

Sigma-Aldrich

Tris(2,3-epoxypropyl) isocyanurate

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Synonym(s):
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione, TGIC, Triglycidyl isocyanurate
Empirical Formula (Hill Notation):
C12H15N3O6
CAS Number:
Molecular Weight:
297.26
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

form

powder

Quality Level

SMILES string

O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4

InChI

1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2

InChI key

OUPZKGBUJRBPGC-UHFFFAOYSA-N

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This Item
114235440825309001
Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 1B - Skin Sens. 1 - STOT RE 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Airborne contact dermatitis due to triglycidylisocyanurate.
A Dooms-Goossens et al.
Contact dermatitis, 21(3), 202-203 (1989-09-01)
U Erikstam et al.
Contact dermatitis, 44(1), 13-17 (2001-01-13)
Triglycidyl isocyanurate (TGIC) is mainly used in polyester-based powder paints, but also in laminates, insulating varnishes, coatings and adhesives. Several cases of contact allergy to TGIC have been reported during the last 10 years. Contact allergy to TGIC has developed
M M Ames et al.
Cancer research, 44(9), 4151-4156 (1984-09-01)
Teroxirone is an experimental triepoxide antitumor agent currently undergoing evaluation in clinical trials. We have developed an assay based on derivatization with diethyldithiocarbamate followed by normal-phase high-performance liquid chromatographic analysis. When 14C-labeled teroxirone is administered to rabbits by rapid i.v.
L Meuleman et al.
Allergy, 54(7), 752-756 (1999-08-12)
The case is presented of a man with allergic contact dermatitis and occupational asthma due to triglycidylisocyanurate (TGIC), which is used as a hardener in thermosetting powder paint. The contact dermatitis was confirmed by patch testing (TGIC 0.5% and 5%
Martin Roff et al.
The Annals of occupational hygiene, 48(3), 257-265 (2004-04-03)
This paper describes workplace dermal exposure measurements that were carried out by the Health and Safety Laboratory as part of the EU RISKOFDERM project to measure dust contamination. Exposure to dry powder spray paints was measured at five sites on

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