381985

Nysted Reagent

20 wt. % suspension in THF

• Synonym(s): cyclo-Dibromodi-μ-methylene[μ-(tetrahydrofuran)]trizinc
• Empirical Formula (Hill Notation): C₆H₁₂Br₂OZn₃
• CAS Number: 41114-59-4
• Molecular Weight: 456.14
• MDL number: MFCD00134567
• PubChem Substance ID: 24863854
• NACRES: NA.22

Properties

• Quality Level: 200
• form: slurry
• reaction suitability: reaction type: C-C Bond Formation
• concentration: 20 wt. % suspension in THF
• density: 1.186 g/mL at 25 °C (lit.)
• SMILES string: C1CCOC1.Br[Zn]C[Zn]C[Zn]Br
• InChI: 1S/C4H8O.2CH2.2BrH.3Zn/c1-2-4-5-3-1;;;;;;;/h1-4H2;2*1H2;2*1H;;;/q;;;;;;2*+1/p-2
• InChI key: CCTHTLJWXPUNGT-UHFFFAOYSA-L

Description

Application

Reactant for:

• Synthesis of amphidinolide T3 using a ring-closing metathesis and asymmetric dihydroxylation strategy
• Methylenation of carbonyl compounds
• Olefination reactions

Useful reagent for the methylenation of ketones and α-ketols.

Packaging

100 g in glass bottle

1 kg in glass bottle

Safety Information

• Pictograms: GHS02,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H319 - H335 - H336 - H351
• Precautionary Statements: P201 - P202 - P210 - P233 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2
• Supplementary Hazards: EUH019
• Storage Class Code: 4.3 - Hazardous materials, which set free flammable gases upon contact with water
• WGK: WGK 3
• Flash Point(F): -14.8 °F
• Flash Point(C): -26 °C