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MilliporeSigma

390089

Dehydroisoandrosterone 3-acetate

97%

Synonym(s):

3-β-Acetoxy-5-androsten-17-one, Prasterone acetate

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About This Item

Empirical Formula (Hill Notation):
C21H30O3
CAS Number:
853-23-6
Molecular Weight:
330.46
EC Number:
212-714-1
MDL number:
MFCD00021119
UNSPSC Code:
12352108
PubChem Substance ID:
24864315
NACRES:
NA.22

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Quality Level

100

assay

97%

form

solid

optical activity

[α]20/D +2.4°, c = 2 in ethanol

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

mp

168-170 °C (lit.)

functional group

ester
ketone

SMILES string

CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CCC4=O)[C@@H]3CC=C2C1

InChI

1S/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/m0/s1

InChI key

NCMZQTLCXHGLOK-ZKHIMWLXSA-N

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1 of 4

This Item
P49902D5297709549
Dehydroisoandrosterone 3-acetate 97%

Sigma-Aldrich

390089

Dehydroisoandrosterone 3-acetate

Pregnenolone acetate 99%

Sigma-Aldrich

P49902

Pregnenolone acetate

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate ≥93% (TLC), powder

Sigma-Aldrich

D5297

Dehydroisoandrosterone 3-sulfate sodium salt dihydrate

Dehydroepiandrosterone-2,2,3,4,4,6-d6 97 atom % D, 98% (CP)

Sigma-Aldrich

709549

Dehydroepiandrosterone-2,2,3,4,4,6-d6

assay

97%

assay

99%

assay

≥93% (TLC)

assay

98% (CP)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

mp

168-170 °C (lit.)

mp

149-152 °C (lit.)

mp

148-149 °C (dec.) (lit.)

mp

149-151 °C

form

solid

form

powder

form

powder

form

powder

optical activity

[α]20/D +2.4°, c = 2 in ethanol

optical activity

[α]20/D +19°, c = 1 in ethanol

optical activity

-

optical activity

-

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

drug control

-

drug control

-

drug control

-

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKBC1708V
MKBC1708
MKAA0715
05009DJ
01011CZ

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M A Graf et al.
Fertility and sterility, 59(4), 761-767 (1993-04-01)
To elucidate changes in gonadotropin secretion pattern in patients with hyperandrogenemic chronic anovulation of various origins. Hyperandrogenemic patients (n = 32), divided into subgroups according to certain clinical and biochemical criteria, and a control group (n = 9) of regularly
Vânia M A Moreira et al.
Steroids, 72(14), 939-948 (2007-09-22)
A series of novel 1H- and 2H-indazole derivatives of the commercially available dehydroepiandrosterone acetate have been synthesized and tested for inhibition of human cytochrome 17alpha-hydroxylase-C(17,20)-lyase (CYP17), androgen receptor (AR) binding affinity, and cytotoxic potential against three prostate cancer (PC) cell
H Shinohara
Experientia, 37(12), 1353-1354 (1981-12-15)
Fragmentation of oocytes was induced in the ovary, via ovulation suppression, by administration of dehydroepiandrosterone acetate (DHA-Ac) to mature cycling rats. The maximal fragmentation ratio, 15.0 +/- 3.2%, was obtained by 10 mg/100 g b.wt/day for 7-day administration of DHA-Ac.
A R Tagliaferro et al.
The Journal of nutrition, 116(10), 1977-1983 (1986-10-01)
Twenty adult Sprague-Dawley outbred rats (10 male and 10 female) were fed a nonpurified diet without or containing dehydroepiandrosterone acetate (DHEA 6 g/kg diet) for 11 w. DHEA-treated animals weighed less than the controls after 6 wk and until the
D C Cumming
Cleveland Clinic journal of medicine, 57(2), 161-166 (1990-03-01)
The effects of estrogenic steroid hormones in women are apparent, but the circulating androgen levels are much higher. Compared with serum estrone and estradiol levels, circulating testosterone levels are five to 10 times higher, androstenedione levels 30 times higher, dehydroepiandrosterone
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