391204

Methyl pipecolinate hydrochloride

97%

• Synonym(s): Methyl 2-piperidinecarboxylate hydrochloride
• Empirical Formula (Hill Notation): C₇H₁₃NO₂ · HCl
• CAS Number: 32559-18-5
• Molecular Weight: 179.64
• MDL number: MFCD00192316
• PubChem Substance ID: 24864365
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• mp: 205 °C (dec.) (lit.)
• SMILES string: Cl.COC(=O)C1CCCCN1
• InChI: 1S/C7H13NO2.ClH/c1-10-7(9)6-4-2-3-5-8-6;/h6,8H,2-5H2,1H3;1H
• InChI key: APCHKWZTSCBBJX-UHFFFAOYSA-N

Description

General description

Methyl pipecolinate hydrochloride is a hydrochloride salt of methyl piperidine-2-carboxylate (methyl pipecolinate). The kinetics of the enzymatic separation of enantiomeric forms of methyl pipecolinate using Candida antarctica Lipase A (CAL-A) has been reported. Its role as catalyst for the standard Diels-Alder reaction has been examined.

Application

Reactant for synthesis of:
A pipecolic linker
Antiviral agents
Aurora and epidermal growth factor receptor kinase inhibitor
Pyrrolidine derivatives via reduction of substituted pyrroles

Reactant for:
Petasis reactions
Decarbonylative radical cyclization of alpha-amino selenoesters upon electrophilic alkenes

Packaging

5, 25 g in glass bottle